Results 51 to 60 of about 44,247 (253)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Data Recovery in Wireless Sensor Networks Based on Low Rank and Short-Term Stability

open access: yesIEEE Access, 2019
The most effective way to reduce the energy consumption of energy-limited wireless sensor networks is to reduce the amount of data collected. However, this will increase the difficulty of data recovery.
Xiaochao Liu   +3 more
doaj   +1 more source

Moving target detection method based on CUR‐RPCA for missing array elements

open access: yesIET Radar, Sonar & Navigation, 2022
Moving target detection performance is seriously affected by missing array elements for multichannel synthetic aperture radar (Multi‐SAR) systems. Meanwhile, there is a contradiction between the accuracy of data recovery and the computational burden in ...
Jianli Shi   +4 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Low-Rank and Sparse Recovery of Human Gait Data

open access: yesSensors, 2020
Due to occlusion or detached markers, information can often be lost while capturing human motion with optical tracking systems. Based on three natural properties of human gait movement, this study presents two different approaches to recover corrupted ...
Kaveh Kamali   +5 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Tensor Decomposition for Salient Object Detection in Images

open access: yesBig Data and Cognitive Computing, 2019
The fundamental challenge of salient object detection is to find the decision boundary that separates the salient object from the background. Low-rank recovery models address this challenge by decomposing an image or image feature-based matrix into a low-
Junxiu Zhou, Yangyang Tao, Xian Liu
doaj   +1 more source

Learning Low-Rank Class-Specific Dictionary and Sparse Intra-Class Variant Dictionary for Face Recognition. [PDF]

open access: yesPLoS ONE, 2015
Face recognition is challenging especially when the images from different persons are similar to each other due to variations in illumination, expression, and occlusion.
Xin Tang   +3 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Home - About - Disclaimer - Privacy