Results 181 to 190 of about 11,850,628 (306)

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Solitary neurocysticercosis mimicking tuberculoma and glioblastoma: A diagnostic challenge in a low-resource setting. [PDF]

Surg Neurol Int
Yousif ME, Mohamed FMA, Mohamed HMB.
europepmc   +1 more source

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

FEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav, Shweta Shweta, Manisha Malhotra, Vikash Maurya, Akhilesh Kumar   +4 more
wiley   +1 more source

Early Detection of Glaucoma and Diabetic Retinopathy in Low-Resource Settings: Barriers and Solutions. [PDF]

J Clin Med
Gupta E, Aung MH, Bowden E.
europepmc   +1 more source

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

FEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima, Kotone Watanabe, Grigorii Sultanakhmetov, Aoi Fukuchi, Keiya Ito, Sawako Shimizu, Taro Saito, Akiko Asada, Kanae Ando   +8 more
wiley   +1 more source

Management of neonatal pyonephrosis in a low-resource setting: a case report. [PDF]

Ann Med Surg (Lond)
Adhikari N, Koirala D, Sapkota R, Mishra B, Paudel N, Mishra D.   +5 more
europepmc   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Successful Transabdominal Cerclage for Recurrent Second-Trimester Loss in a Low-Resource Environment: A Case Report. [PDF]

Case Rep Obstet Gynecol
Djokoto RMK, Agana EA, Nduroh KA, Arthur-Komeh J, Adarkwa O, Sam-Awortwi WK, Opare-Addo KA, Vormawor AP, Ofori AA.   +8 more
europepmc   +1 more source

Self‐Regulated Learning Meets AI: Reinterpreting Self‐Regulation, Co‐Regulation, and Socially Shared Regulation in Human–AI Interaction

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley   +1 more source

Gestational choriocarcinoma following an ectopic pregnancy: A diagnostic dilemma in low-resource settings. [PDF]

Radiol Case Rep
Dusuri E, Arkorful J, Gyamfi BA, Larbi CGA, Amaning OA, Agyei BA.   +5 more
europepmc   +1 more source