Results 231 to 240 of about 13,073,421 (310)

Gastric Adenocarcinoma Presenting as Pseudoachalasia: A Case Report from a Low-Resource Setting. [PDF]

Int Med Case Rep J
Mohamud EH, Ahmed LH, Nor AA, Muse AA, Elmi AS.   +4 more
europepmc   +1 more source

Validation of a Cellular Imaging‐Based Method as a Potential Biomarker for SPG4 Hereditary Spastic Paraplegia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Hereditary Spastic Paraplegia (HSP) comprises a group of rare genetic diseases characterized by length‐dependent axonal degeneration of the corticospinal tracts and dorsal columns, whose main clinical feature is spastic gait. Pathogenic variants in the SPG4 gene cause Spastic Paraplegia Type 4 (SPG4‐HSP), the most common form of HSP.
Gaia Fattorini, Valerio Licursi, Gianmarco Dalla Zanna, Flavio Dal Canto, Melissa Barghigiani, Nunzio Setola, Salvatore Rossi, Antonio Funcis, Filippo M. Santorelli, Gabriella Silvestri, Carlo Casali, Francesca Sardina, Cinzia Rinaldo   +12 more
wiley   +1 more source

Non-operative management of acute appendicitis is not readily generalisable to Honduras: a viewpoint from a low-resource setting. [PDF]

J Glob Health
Valladares MR, Zuniga P, Flores M, Pauta VL, Mandujano CC.   +4 more
europepmc   +1 more source

Augmenting and Assaying Nav1.1 Protein Quantity for Dravet Syndrome Therapy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Dravet Syndrome (DS) is a developmental and epileptic encephalopathy predominantly caused by heterozygous loss‐of‐function variants in SCN1A, which encodes Nav1.1. Conserved upstream open reading frames (uORFs) in SCN1A were validated to regulate translation in reporter assays, demonstrating the therapeutic viability of increasing Nav1.1 from ...
Aiswarya Saravanan, Jordan Safran, Anna Loughman, Grace Lin, Shivanshi Vaid, Dana Allababidi, Peter M. Tessier, Louis T. Dang   +7 more
wiley   +1 more source

Lutembacher's syndrome presenting in the third trimester: a multidisciplinary challenge in a low-resource setting. [PDF]

BMC Cardiovasc Disord
Sidiqi AW, Rahbeen A, Noorandish M, Naibkhil HR, Nassery M, Sidiqi K, Rahimi K.   +6 more
europepmc   +1 more source

Evaluation of Dried Plasma Spot‐Based Quantification of Glial Fibrillary Acidic Protein as a Disease‐Associated Biomarker in Neuromyelitis Optica Spectrum Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the diagnostic accuracy of glial fibrillary acidic protein (GFAP) measured in dried plasma spots versus conventional plasma‐ and serum‐GFAP testing for assessment of disease severity in aquaporin‐4 immunoglobulin G–positive neuromyelitis optica spectrum disorder (AQP4‐IgG+ NMOSD).
Felix Wohlrab, Evelyn Alvarez, Roua Hamdi, Bingqing Zhang, Hayeun Ji, Niyati Jhaveri, Patrick Schindler, Pedro Sanchez, Pia S. Sperber, Tanja Schmitz‐Hübsch, Frederike C. Oertel, Nisa Vorasoot, Najib Kissani, Falko Böhringer, Jens Kuhle, Anne‐Katrin Pröbstel, Xiao‐Jun Ma, Péter Körtvelyessy, Patrick Waters, Friedemann Paul   +19 more
wiley   +1 more source

Neonatal Ventilation Training Using a Low-Cost, High-Fidelity Simulator in a Low-Resource Setting: A Randomized Clinical Trial.

JAMA Netw Open
Mocellin D, Maglio S, Nanyaro MW, Belardi P, Borellini M, Shayo EH, Ferrari A, Mfaume B, Ntinginya N, Tognarelli S, Menciassi A.   +10 more
europepmc   +1 more source

To: Diagnostic accuracy of lung ultrasound in children with respiratory pathology admitted in a pediatric intensive care unit of a low-resource setting: a single-center experience. [PDF]

Crit Care Sci
Khan MS, Chaari A.
europepmc   +1 more source

Impact of Age on the Diagnostic Yield of Routine EEG in People With Childhood or Juvenile Absence Epilepsy: A Cross‐Sectional Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background We aimed to identify the proportion of individuals with a confirmed diagnosis of childhood absence epilepsy (CAE) or juvenile absence epilepsy (JAE) who show a negative routine EEG (rEEG), and to determine the main factors associated with this finding.
Francesco Fortunato, Alessia Giugno, Miriam Sturniolo, Enrico Fratto, Pio Zoleo, Francesca Felicia Operto, Ilaria Sammarra, Antonio Gambardella   +7 more
wiley   +1 more source

Catastrophic health expenditures associated with single admission for paediatric surgery in a low-resource setting: a multicentre study. [PDF]

BMJ Glob Health
Sholadoye TT, Williams OM, Elebute OA, Ekwunife OH, Alakaloko F, Abdur-Rahman L, Kruger D, Libhaber E, Kachapila M, Oyegbola C, Oyewande OA, Bhangu A, Harrison EM, Nepogodiev D, Glasbey JC, Morton D, Ameh EA, Ademuyiwa AO, CATERPILLAR study group.   +18 more
europepmc   +1 more source