Results 101 to 110 of about 1,578,666 (279)

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Tonga: Economic Survey 2009 [PDF]

, 2015
The Tongan economy was well on its way to recovery from the effects of the riots and the oversized rise in public sector salaries of 2005 when it was hit by three new shocks: an inflation surge in 2007-08 due to price rises for imported food and fuels ...
De Fontenay, Patrick, Utoikamanu, Siosiua T.T.   +1 more
core  

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Three centuries of multi-storied St. Petersburg

E3S Web of Conferences, 2018
The article is devoted to assessment of the role of high-rise buildings in the St. Petersburg historic city’s ensemble. Features of formation of city architectural look, the conditions of city typical silhouette’s appearance which is characterized by the
Lavrov Leonid, Perov Fedor, Eremeeva Aleksandra, Temnov Vladimir   +3 more
doaj   +1 more source

An integrated geoscience modelling approach to ground water and coastal flood risk [PDF]

, 2011
Understanding flood risk in Morayshire has required the adoption of a holistic work programme that brought together a multidisciplinary scientific team who used a variety of modelling techniques to investigate groundwater and coastal flood risk within ...
Auton, Clive, Hughes, A., MacDonald, A., Reeves, H.   +3 more
core  

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Construction of energy-efficient low-rise buildings by frame-panel sip technology

Bulletin of Prydniprovs’ka State Academy of Civil Engineering and Architecture, 2019
Постановка проблеми. Будівництво малоповерхових споруд в Україні із застосуванням СІПтехнологій дозволяє знизити тривалість зведення будівель, зробити їх екологічними, міцними і надійними, а також зменшити їх вартість. У зв’язку з цим в Україні актуальними постають енергоефективні малоповерхові будівлі швидкого зведення за каркасно-панельною СІП ...
Diachenko, L. Yu., Diachenko, O. S.
openaire   +3 more sources

Design of space-type electronic power transformers [PDF]

Both open and encapsulated varieties of high reliability, low weight, and high efficiency moderate and high voltage transformers were investigated to determine the advantages and limitations of their construction in the ranges of power and voltage ...
Ahearn, J. F., Lagadinos, J. C.
core   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Features of urban planning of emergency low-rise housing construction

Bulletin of Kazakh Leading Academy of Architecture and Construction, 2020
This article analyzes the architectural, urban, social and economic causes of the emergence and development of spontaneous low-rise housing development, which is especially typical for cities in developing countries. It also provides a classification of the types of buildings, such as architectural vernacular, spontaneous cottage towns, ghetto, and ...
openaire   +1 more source