Results 51 to 60 of about 3,420,502 (281)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Phase space diffusion and low temperature aging

, 1995
We study the dynamical evolution of a system with a phase space consisting of configurations with random energies. The dynamics we use is of Glauber type.
Barrat, A., Mézard, M.
core   +3 more sources

Low-temperature excitations within the Bethe approximation [PDF]

, 2013
We propose the variational quantum cavity method to construct a minimal energy subspace of wave vectors that are used to obtain some upper bounds for the energy cost of the low-temperature excitations. Given a trial wave function we use the cavity method
Biazzo, I., Ramezanpour, A.
core   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Fractionation of nitrogen isotopes in the enzymatic deamination of alanine: an insight into the quantitative evaluation of anaerobic metabolism in ecosystems

Progress in Earth and Planetary Science
Nitrogen isotope ratios of amino acids have been employed as a tool for illustrating the resource utilization of organisms and the trophic transfer between organisms in food webs.
Yuko Takizawa, Hyuntae Choi, Mio Shibuya, Nayeon Park, Prarthana S. Dharampal, Shawn A. Steffan, Yoshito Chikaraishi   +6 more
doaj   +1 more source

Antiferromagnets at Low Temperatures [PDF]

AIP Conference Proceedings, 2011
The low-temperature properties of the Heisenberg antiferromagnet in 2+1 space-time dimensions are analyzed within the framework of effective Lagrangians. It is shown that the magnon-magnon interaction is very weak and repulsive, manifesting itself through a term proportional to five powers of the temperature in the pressure.
C. P. Hofmann, Alejandro Ayala, Guillermo Contreras, Ildefonso Leon, Pedro Podesta   +4 more
openaire   +2 more sources

Bulk viscosity of low-temperature strongly interacting matter [PDF]

, 2011
We study the bulk viscosity of a pion gas in unitarized Chiral Perturbation Theory at low and moderate temperatures, below any phase transition to a quark-gluon plasma phase.
Aamodt, Antonio Dobado, Aoki, Arnold, Chakraborty, Chen, Csernai, Davesne, Dobado, Dobado, Dobado, Dobado, Felipe J. Llanes-Estrada, Fernandez-Fraile, Gasser, Gavin, Gomez Nicola, Juan M. Torres-Rincon, Karsch, Lu, Prakash, Song, Wiranata   +22 more
core   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Surface related laser induced white emission of Cr:YAG ceramic

Scientific Reports, 2021
In this work we report the white light emission in transparent Cr:YAG ceramic pellet upon irradiation with focused beam of CW infrared laser diode. It was found that this phenomenon is specifically related to interaction of laser beam with a surface of ...
M. Chaika, R. Tomala, W. Strek
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source