Results 81 to 90 of about 956,942 (290)
Low velocity impact analysis with NASTRAN [PDF]
A nonlinear elastic force-displacement relationship is used to calculate the transient impact force and local deformation at the point of contact between impactor and target.
Aiello, Robert A. +2 more
core +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Wave propagation in graphite/epoxy laminates due to impact [PDF]
The low velocity impact response of graphite-epoxy laminates is investigated theoretically and experimentally. A nine-node isoparametric finite element in conjunction with an empirical contact law was used for the theoretical investigation.
Sun, C. T., Tan, T. M.
core +1 more source
Application of Ion Cyclotron Resonance to the Study of Inelastic Excitation by Low-Energy Electrons [PDF]
, 1969 The geometry of the resonance cell employed for ion cyclotron resonance spectroscopy (1-3) is ideally suited for studying inelastic excitation by low-energy electrons.
Beauchamp, J. L., Ridge, Douglas P.
core +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Analysis and modelization of lightweight structures subjected to impact [PDF]
, 2008 Mechanics of Advanced Materials research group (Department of Continuum Mechanics and Structural Analysis) of the University Carlos III of Madrid (Spain) offers their experience in the analysis and modelization of high and low velocity impact behaviour ...
Barbero Pozuelo, Enrique +1 more
core +1 more source
Nucleosynthesis in Rotating massive stars and Abundances in the Early Galaxy [PDF]
, 2009 We discuss three effects of axial rotation at low metallicity. The first one is the mixing of the chemical species which is predicted to be more efficient in low metallicity environments. A consequence is the production of important quantities of primary
Akerman +23 more
core +1 more source