Results 61 to 70 of about 10,491,704 (178)

Awareness and Knowledge of Low Anterior Resection Syndrome (Lars) in Colorectal Surgeons: A Cross-sectional Survey [PDF]

, 2020
Abstract Background More than 50% patients suffered from low anterior resection syndrome (LARS) after low anterior resection, and their quality of life is predominantly determined by colorectal surgeons’ awareness and knowledge of LARS. We conducted the survey to find out the weakness in the management of patients' functional recovery after ...
Sen Hou, Fan Liu, Peng Guo, Yingjiang Ye
openaire   +1 more source

Redefining Low Anterior Resection Syndrome

, 2021
Low Anterior Resection Syndrome (LARS) is used to describe bowel dysfunction which patients experience after rectal cancer treatment. There is interest in the field as the accumulating evidence reinforces that LARS is common.
Keane, Celia
core  

Low Anterior Resection Syndrome: Pathophysiology, Risk Factors, and Current Management

The Ewha Medical Journal, 2022
Low anterior resection syndrome (LARS) is a condition of anorectal dysfunction that occurs frequently following anal sphincter-preserving surgery for rectal cancer and can reduce the quality of life. In this review,
Seung Mi Yeo, Gyung Mo Son
doaj   +1 more source

Low Anterior Resection Syndrome (LARS)

Rectal cancer surgery has undergone significant advancements, with a shift towards sphincter-sparing operations due to improved surgical techniques and neoadjuvant treatments. However, this has given rise to low anterior resection syndrome (LARS), characterised by various bowel functional abnormalities adversely impacting patients’ quality of life ...
Sotirios-Georgios Popeskou, Dimitrios Christoforidis   +1 more
openaire   +1 more source

Reduced Expression of Magnesium Transport Proteins in the Distal Convoluted Tubule of Clcnkb‐Deficient Mice May Explain Urinary Magnesium Wasting in Classical Bartter Syndrome

Acta Physiologica, Volume 242, Issue 9, September 2026.
ABSTRACT Aim The kidney thick ascending limb (TAL) plays a key role in the transport of sodium, chloride, potassium, calcium, and magnesium. Bartter syndrome is a hypokalemic, salt‐losing tubulopathy caused by impaired TAL function. Pathogenic variants in SLC12A1 or KCNJ1 cause antenatal Bartter syndrome, and variants in CLCNKB result in classical ...
Marleen L. A. Kortenoeven, Milos Bogdanovic, Ida Appel, Karsten Skjødt, Ernst‐Martin Fuchtbauer, Kirsten Madsen, Lars Lund, Régine Chambrey, Dominique Eladari, R. Todd Alexander, Christian A. Hübner, J. Christopher Hennings, Henrik Dimke   +12 more
wiley   +1 more source

The Role of Percutaneous Tibial Nerve Stimulation (PTNS) in Low Anterior Resection Syndrome (LARS): A Systematic Review and Meta-analysis

Journal of Gastrointestinal Cancer, 2023
The aim of the present study was to evaluate the pooled efficacy of percutaneous tibial nerve stimulation (PTNS) in patients with low anterior resection syndrome (LARS).This study was based on the Cochrane Handbook for Systematic Reviews of Interventions and the PRISMA guidelines.
Stavros Chrysovalantis Liapis, Ioannis Baloyiannis, Konstantinos Perivoliotis, Dimitrios Lytras, Georgios Theodoropoulos, Georgios Tzovaras   +5 more
openaire   +3 more sources

Clinical Trial: Effectiveness and Safety of a Novel Anal Insert Device for Treatment of Faecal Incontinence

Alimentary Pharmacology &Therapeutics, Volume 64, Issue 5, Page 603-614, September 2026.
StaySure is a novel anal insert device that safely and effectively treats medically refractory faecal incontinence. Treatment reduced incontinence episodes by 69%, improved quality of life beyond clinically meaningful thresholds, and was well tolerated with no treatment‐related serious adverse events. ABSTRACT Background Treatment options for medically‐
Adil E. Bharucha, Ramesh Lamichhane, Joel G. Fletcher, Nicholas R. Oblizajek, Misha Gautam, Kent R. Bailey, Lawrence A. Szarka   +6 more
wiley   +1 more source

Effectiveness of transanal irrigation in low anterior resection syndrome [PDF]

Background: Low anterior resection syndrome (LARS) is a frequent issue leading to bowel dysfunction after anterior resection surgery. NICE guidelines state that there is limited research around the management of LARS.
Curran, Karen, Hopkinson‐Woolley, Digby, Boffin, Helen, Singh, Sandeep, Doyle, Rebecca, Gorissen, Kim, Jauhari, Shreya   +6 more
core   +1 more source

Low anterior resection syndrome after right‐ and left‐sided resections for colonic cancer

BJS Open, 2019
Background This population‐based cohort study aimed to evaluate occurrence of low anterior resection syndrome (LARS) and correlate this to health‐related quality of life in patients who had undergone segmental colonic resection for colonic cancer in the ...
C. Buchli, A. Martling, A. Sjövall
doaj   +1 more source

Sexual dysfunction outcomes and reporting disparities after multimodal treatment for rectal cancer: A systematic review and narrative synthesis

Colorectal Disease, Volume 28, Issue 9, September 2026.
Abstract Background Sexual dysfunction is a recognised adverse outcome after rectal cancer treatments, yet reporting is predominantly male‐focused, with female sexual dysfunction less consistently assessed or reported. This systematic review aimed to assess sexual health domains studied, examine sex‐based reporting disparities, and identify limitations
Vignesh Lakshmanan, Jennifer Waterman, Alun Meggy, Jared Torkington, Julie A. Cornish   +4 more
wiley   +1 more source