Results 101 to 110 of about 23,670 (281)

Long term persistence and risk factors for anorectal symptoms following low anterior resection for rectal cancer

BMC Gastroenterology
Background Rectal cancer is commonly treated by chemoradiation therapy, followed by the low anterior resection anal sphincter-preserving surgery, with a temporary protecting ileostomy.
E. Koifman, M. Armoni, Y. Gorelik, A. Harbi, Y. Streltsin, S. D. Duek, R. Brun, Y. Mazor   +7 more
doaj   +1 more source

Score assessment and treatment in patients presenting with low anterior resection syndrome after sphincter-sparing rectal cancer surgery

International Journal of Colorectal Disease
Sphincter-sparing low anterior resection (SSLAR) with neoadjuvant radio-chemotherapy has been developed to avoid abdomino-perineal amputation and permanent colostomy in patients with low rectal cancer. However, many patients develop symptoms known as low anterior resection syndrome (LARS), including fecal urgency, incontinence, and a sensation of ...
Sguinzi, R., Fiechter, J., Bafumi, L., Gremaud, B., Geng, B., Janiak, P., Bühler, L., Egger, B.   +7 more
openaire   +2 more sources

Evaluating the task‐specificity model of verbal memory: Regional volumetric analyses in temporal lobe epilepsy with hippocampal sclerosis

Epilepsia Open, EarlyView.
Abstract Objective Verbal memory tasks differ in their cognitive demands and may rely on distinct left medial temporal structures. One model holds that verbal delayed recall is hippocampal dependent, whereas verbal paired associate learning relies on adjacent rhinal cortex.
Andy Sitoh, David Weintrob, Jacqueline F. I. Anderson, Heath R. Pardoe, Marie F. O'Shea, Graeme D. Jackson, Piero Perucca, Chris Tailby   +7 more
wiley   +1 more source

Sphincter-saving surgery for failed organ preservation after a neoadjuvant therapy and radiation boost: A surgeon's perspective

BMC Gastroenterology
Purpose This study investigates the functional outcomes of patients with low rectal cancer undergoing inter-sphincteric resection (ISR) following brachytherapy boost radiotherapy (BoRT), compared to those who underwent ISR after standard ...
Sanjay Singh, Abdeali Saif Arif Kaderi, Mufaddal Kazi, Ashwin Desouza, Ankit Sharma, Suman Kumar Ankathi, Avanish Saklani   +6 more
doaj   +1 more source

Randomized clinical trial of prophylactic transanal irrigation versus supportive therapy to prevent symptoms of low anterior resection syndrome after rectal resection

BJS Open, 2019
Background Low anterior resection syndrome (LARS) is a frequent problem after rectal resection. Transanal irrigation (TAI) has been suggested as an effective treatment in patients who have developed LARS.
H. R. Rosen, W. Kneist, A. Fürst, G. Krämer, J. Hebenstreit, J. F. Schiemer   +5 more
doaj   +1 more source

Prediction of treatment response in infantile epileptic spasms syndrome using EEG phase–amplitude coupling

Epilepsia Open, EarlyView.
Abstract Objective Treatment selection for infantile epileptic spasms syndrome (IESS) is complex and multifaceted, and currently no electroencephalogram (EEG) biomarkers can guide this decision by predicting treatment response. We tested the predictive value of phase–amplitude coupling (PAC) as IESS patients are known to have elevated PAC.
Soudeh Mostaghimi, Marco A. Pinto‐Orellana, Nathaniel Green, Daniel W. Shrey, Makoto Miyakoshi, Shaun A. Hussain, Beth A. Lopour   +6 more
wiley   +1 more source

Neuroanatomical correlates of neuropsychological dysfunction in pediatric pharmacoresistant epilepsy due to focal cortical dysplasia type II

Epilepsia Open, EarlyView.
Abstract Objective Children and adolescents with pharmacoresistant epilepsy (PRE) show marked individual cognitive and emotional variability not fully accounted for by demographic or clinical variables. This exploratory pilot study characterizes neuroanatomical abnormalities and their relationships with neuropsychological functioning in a pediatric ...
Ana Arenivas, Spencer Morris, Brittany Lapin, Yadi Li, Lisa Ferguson, Stephen E. Jones, Ingmar Blümcke, Imad Najm, Robyn M. Busch, Zhong Irene Wang   +9 more
wiley   +1 more source

Clinical Vignette: A rare pericallosal lipoma presenting with Lennox–Gastaut syndrome and a remarkable response to valproic acid

Epileptic Disorders, EarlyView.
Rainier Mark Loidor L. Rapal, Hok Leong Chin, Douglas Nordli III   +2 more
wiley   +1 more source

Long-term electroacupuncture for low anterior resection syndrome in postoperative rectal cancer patients: case reports

Frontiers in Medicine
This study reports two cases of rectal cancer patients who developed low anterior resection Syndrome (LARS) following rectal cancer surgery. Both patients presented with significant bowel dysfunction, including frequent defecation, urgency, fecal ...
Wenna Li, Wenna Li, Ming Yang, Ming Yang, Jinchang Huang, Jinchang Huang, Qiaoli Zhang, Qiaoli Zhang   +7 more
doaj   +1 more source

A multilevel perspective on MSH6‐associated Lynch syndrome: Integrating molecular, biological, and clinical insights

International Journal of Cancer, EarlyView.
Abstract Lynch syndrome (LS) is the most common hereditary colorectal cancer syndrome, caused by a germline pathogenic variant in one of the mismatch repair (MMR) genes. Among these, MSH6‐associated LS represents a distinct subtype with unique molecular and clinical characteristics.
Salwa Ben Yahia, Anne‐Sophie van der Werf‐'t Lam, Madalina Cabuta, Maartje Nielsen, Noah C. Helderman   +4 more
wiley   +1 more source