Results 131 to 140 of about 10,906,631 (237)

Ultrasound‐Activatable Piezoelectric Hydrogel Reprograms Mitochondrial Epigenetics for Osteoarthritis Therapy via the mTOR/GATD3A Axis

Advanced Science, EarlyView.
An ultrasound‐activatable piezoelectric hydrogel reprograms chondrocyte mitochondrial epigenetics via the mTOR/GATD3A axis, clearing damaged mitochondria and alleviating osteoarthritis progression in both mouse models and human cartilage explants. ABSTRACT The avascular nature of cartilage hinders drug delivery for osteoarthritis (OA) therapy.
Hui Zheng, Pengfei Yan, Peng Liu, Chang Yan, Mengqi Zhao, Zuyong Wang, Chao Ma, Rongkai Zhang, Xi Cui, Swee Hin Teoh   +9 more
wiley   +1 more source

Virtual reality for chronic primary low back pain in adults: systematic review protocol. [PDF]

Syst Rev
Schäfer A, Kaiser U, Elser A, Kopkow C, Elsner B.   +4 more
europepmc   +1 more source

Ultra‐Radiostable Covalent Conformationally Interlocked Networks Enabling a Universal Radiometal‐Labeling Platform for Cancer Radioembolization

Advanced Science, EarlyView.
Conjugated poly(imide dioxime)‐based microspheres establish a radiometal coordination‐driven conformational interlocked network with ultra‐high radiostability. This platform enables low‐temperature, multi‐radionuclide labeling for SPECT/PET/MRI imaging and radionuclide therapy. Mechanistic insights from EXAFS and DFT reveal enhanced stability, while in
Xiao Xu, Zhenwen Zhao, Yangjie Wang, Zhigang Liu, Zhijie Liu, Xiaoling Li, Zhichen Mao, Lu Xu, Gan Lin, Gang Liu, Hongjuan Ma   +10 more
wiley   +1 more source

Sex Differences in Experiencing and Reporting Low Back Pain Using Standardised Questionnaires: A Cross-Sectional Study. [PDF]

Musculoskeletal Care
Santos Ferreira FS, Colmenarez Espinoza AN, Neves Dos Santos AC, da Silva Santos V, Herzer MF, Aline de Oliveira Ribeiro J, da Silva Leonardo I, Brandt de Macedo AC.   +7 more
europepmc   +1 more source

HMGCR‐Driven Cholesterol Metabolism Promotes Osteoarthritis Progression by Accelerating Synovial Fibroblast Senescence

Advanced Science, EarlyView.
In the pathological context of osteoarthritis (OA), the phosphorylation of AKT1 at Ser473 enhances its binding to Lys140 of Insig1, which facilitates the formation of AKT1–Insig1 complex. Subsequently, the activation of AKT1 promotes the phosphorylation of Insig1 at Ser189, potentially enhancing the dissociation of Insig1 from sterol regulatory element‑
Xiaoqi Zhang, Siru Zhou, Xi Liu, Wei Xiang, Xiuqin Peng, Yu Tian, Song Li, Hailin Wang, Bo Liao, Shunzheng Fang, Runze Jin, Jinhui Wu, Chuanqing Bai, Wei Zhang, Bo Huang, Bingfei Li, Lifeng Chen, Lin Chen, Bin Zhang, Zhenhong Ni   +19 more
wiley   +1 more source

Low back pain and menopause

Journal of Mid-Life Health, 2019
Annil Mahajan, Ranu Patni, Somnath Verma
doaj   +1 more source

Effects of musculoskeletal expert input on low back pain outcomes: A randomised controlled trial. [PDF]

PLoS One
Mathieu J, Beauséjour M, Dupèbe W, Châtillon CÉ, O'Shaughnessy J, Tétreau C, Hincapié CA, Schweinhardt P, Descarreaux M, Marchand AA.   +9 more
europepmc   +1 more source

Absorption of Broadband Low‐Frequency Sound Beyond the Thermodynamics Limit: An Acoustic Resonator With Magnetic Bearing

Advanced Science, EarlyView.
This work presents a magnetic‐bearing acoustic resonator that overcomes the thermodynamics limit of sound absorption. By introducing tunable negative stiffness, it achieves broadband low‐frequency absorption within a compact cavity, far exceeding the performance achievable by classic mass‐tuned designs.
Ying Hu, Zhe Zhang, Bohua Huang, Xue Han, Hallam Bastin Kilcoyne, Lixi Huang   +5 more
wiley   +1 more source

Interventional Pain Management for Low Back Pain

Apollo Medicine, 2008
K J Choudhury
doaj   +1 more source

Methodological Concerns Regarding the Bayesian Network Meta-Analysis of Telerehabilitation for Chronic Low Back Pain. [PDF]

J Med Internet Res
Tuersun A, Ma G.
europepmc   +1 more source