Results 251 to 260 of about 1,363,878 (335)

Advances and Strategies in Enhancing mRNA Cancer Vaccines

open access: yesAdvanced Materials, EarlyView.
Messenger RNA (mRNA) vaccines offer a powerful approach for cancer immunotherapy, but their clinical impact remains limited by delivery challenges and suboptimal immune activation. This review discusses key biological barriers and design strategies—including structural optimization, immunomodulation, organ targeting delivery, and advanced nanocarriers ...
Miao Zhang   +4 more
wiley   +1 more source

Autonomous Implants

open access: yesAdvanced Materials, EarlyView.
An ideal implant should mimic native tissues such that it can integrate, sense, heal, and continue to function, i.e., be autonomous. Although early, there are good steps taken in this way, e.g., the development of stimuli‐responsive, self‐powering, self‐actuating, self‐healing, self‐regenerating, and self‐aware implants.
Jagan Mohan Dodda   +5 more
wiley   +1 more source

Cost-effectiveness of exercise therapy in the treatment of non-specific neck pain and low back pain: a systematic review with meta-analysis

open access: yesBritish Journal of Sports Medicine, 2018
G. Miyamoto   +4 more
semanticscholar   +1 more source

Multi‐Scale Modeling of a 3D Soft Magnetoelectric Patch for Wireless Nerve Stimulation

open access: yesAdvanced Materials Interfaces, EarlyView.
Core‐shell, magnetoelectric nanoparticles (MENPs) can serve as wireless electric nano‐sources, thanks to their ability to generate high levels of electricity, when stimulated by a human‐safe external magnetic field. By combining MENPs with soft, biocompatible polymeric matrices and optimizing its composite configuration and electrical behavior via ...
Giulia Suarato   +6 more
wiley   +1 more source

Citrate‐Enhanced PCL Scaffolds for Bone Tissue Engineering

open access: yesAdvanced Materials Interfaces, EarlyView.
This study investigates citrate‐enhanced polycaprolactone (PCL) scaffolds designed for bone tissue engineering. Utilizing 3D printing technology, four scaffold patterns (triple hexagon, grid, gyroid, zigzag) are evaluated for mechanical properties, cellular proliferation, osteogenic differentiation, and gene expression.
Muge Musmula   +6 more
wiley   +1 more source

Damage Microenvironment Guided Responsive Smart Hydrogel Design for Self‐Regenerative Repair in Chronic Wound Healing

open access: yesAdvanced Materials Interfaces, EarlyView.
Chronic wounds remain a major therapeutic challenge, with VEGF applications hindered by rapid degradation and systemic side effects. Here, a dual‐responsive chitosan–gelatin hydrogel is reported, functionalized with dopamine, glutathione, and MMP‐sensitive motifs, enabling spatiotemporally controlled VEGF release and enhanced biocompatibility, thereby ...
Zhenghui Xiong   +5 more
wiley   +1 more source

Prevention of Low Back Pain: A Systematic Review and Meta-analysis.

open access: yesJAMA Internal Medicine, 2016
D. Steffens   +7 more
semanticscholar   +1 more source

Polypeptide Nanotoroids Formed on Substrate via Solvent Evaporation‐Induced Self‐Assembly

open access: yesAdvanced Materials Interfaces, EarlyView.
Polypeptide nanotoroids are formed on substrates via a solvent evaporation‐induced self‐assembly process, which is driven by the increased interfacial energy of the initially formed polypeptide nanorods upon their exposure to air during the solvent evaporation.
Qi Guo   +3 more
wiley   +1 more source

Fear of movement/(re)injury in chronic low back pain and its relation to behavioral performance

open access: yesPain, 1995
J. Jong   +5 more
semanticscholar   +1 more source

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