Results 271 to 280 of about 780,904 (321)

Nephronectin (NPNT) is a Crucial Determinant of Idiopathic Pulmonary Fibrosis: Modulating Cellular Senescence via the ITGA3/YAP1 Signaling Axis

Advanced Science, EarlyView.
Through a comprehensive multi‐omics analysis, this study identifies a marked reduction in Nephronectin (NPNT) expression within fibrotic lung tissue. This reduction impairs the binding capability to the ITGA3 receptor, consequently causing YAP1 to persist in the cytoplasm, where it undergoes degradation.
Jiayu Guo, Yan Wang, Qiudi Liu, Zhaoyang Luo, Xiaomu Tian, Yuquan Wang, Yang Liu, Zhiwei Ning, Yingying Guo, Huiying Gao, Xinyue Wang, Jinglong Feng, Mengmeng Liu, Dina Saifullina, Yixin Zhang, Tengfei Pan, Yu Bian, Tao Ban, Tianyu Li, Yunyan Gu, Haihai Liang   +20 more
wiley   +1 more source

Persistent pain signaling and stress response in a mouse model of inflammatory low back pain. [PDF]

Pain Rep
Motohashi H, Yamaji Y, Mori K, Washizu S, Hoshino O, Fujimoto K, Kanazawa S, Minegishi Y, Ota N, Mori T, Segi-Nishida E.   +10 more
europepmc   +1 more source

Bionic Nanostructures Create Mechanical Signals to Mediate the Composite Structural Bone Regeneration Through Multi‐System Regulation

Advanced Science, EarlyView.
Inspired by the structural and functional characteristics of bone, bionic nanomaterials combined with nanotechnology can more accurately replicate stem cell niches, enabling the design of bone tissue engineering scaffolds with diverse nanoscale properties to promote stem cell migration, proliferation, and differentiation. This precise control over stem
Yangfan Pei, Yihan Wang, Jingxia Chen, Jing Zhou, Yuzhu Han, Xiuyu Liu, Siyu Chen, Sheng Chen, Dixin He, Yunxiao Wu, Huixin Lv, Yanmin Zhou   +11 more
wiley   +1 more source

Joint Association of Occupational and Leisure-Time Physical Activity With Low Back Pain in Korean Adults. [PDF]

Musculoskeletal Care
Yim S, Park D.
europepmc   +1 more source

A Full‐Range Proximity‐Tactile Sensor Based on Multimodal Perception Fusion for Minimally Invasive Surgical Robots

Advanced Science, EarlyView.
A full‐range proximity‐tactile sensing module is developed for safe operation of surgical robots, which performs multimodal fusion perception through ultrasonic sensor for long‐range proximity detection, capacitive sensor for close‐range proximity sensing, and triboelectric sensor for tactile sensing.
Dongsheng Li, Tianci Ji, Yuyang Sun, Zhongbin Zhang, Aomen Li, Mengjiao Qu, Dongze Lv, Jin Xie, Huicong Liu   +8 more
wiley   +1 more source

Biopsychosocial Strategies for Alleviating Low Back Pain in Late Mothers: A Systematic Review. [PDF]

Healthcare (Basel)
Bulathwatta DT, Treppner M, Januszkiewicz M, Głowacka P, Borchet J, Bulathwatta A, Bidzan M.   +6 more
europepmc   +1 more source

Glucose‐Responsive and Analgesic Gel for Diabetic Subcutaneous Abscess Treatment by Simultaneously Boosting Photodynamic Therapy and Relieving Hypoxia

Advanced Science, EarlyView.
The work constructs a glucose‐triggered gel for diabetic abscess treatment. The results demonstrate that the gel catalyzes glucose into oxygen, alleviates the hypoxia, and ensures sufficient ROS generation to combat pathogenic bacteria. Simultaneously, borneol within the gel can enhance the antibacterial activity of ROS and alleviate pain in patients ...
Bin Huang, Honglin An, Jianfeng Chu, Shiqi Ke, Jing Ke, Yiman Qiu, Jieping Zhang, Hanqi Zhu, Jiahui Lin, Minguang Yang, Dongliang Yang, Xuejiao Song, Weilin Liu   +12 more
wiley   +1 more source

Motivation to exercise in patients with chronic low back pain. [PDF]

BMC Musculoskelet Disord
Nevelikova M, Zlamal F, Dosbaba F, Su JJ, Batalik L.   +4 more
europepmc   +1 more source

Parvalbumin Interneuron‐Dependent Hippocampal Neurogenesis Evoked by Prolonged Rhythmic Light Flicker

Advanced Science, EarlyView.
This study demonstrates that prolonged rhythmic 40 Hz light flicker enhances spatial learning by stimulating PV interneuron‐dependent neurogenesis. The light flicker selectively activates PV interneurons, which enhances GABAergic support for the integration of immature neurons in the adult dentate gyrus.
Hai Yan, Yunxuan Wang, Xufan Deng, Shiyu Wu, Yifan Pan, Jun Du, Mei Yu, Bo Liu, Huimei Wang, Zhengyu Zhang, Jinghong Chen, Shuifa Chen, Yizheng Wang, Tara Walker, Perry Bartlett, Jun Ju, Sheng‐Tao Hou   +16 more
wiley   +1 more source

One-Page Patient Fact Sheets for Low Back Pain in Primary Care: A Randomized Clinical Trial.

JAMA Netw Open
Longtin C, Chang JR, Hersch J, Sharma S, Ferraro MC, Rizzo RRN, McBride J, Wong AYL, Maher CG, Guppy M, McAuley JH, Traeger AC.   +11 more
europepmc   +1 more source