Results 331 to 340 of about 1,915,285 (391)

Diurnal Release of Airborne Pathogen Spores in Greenhouses via the Synergistic Effects of Relative Humidity and Wind

open access: yesAdvanced Science, EarlyView.
Day‐night cycles trigger sharp relative humidity (RH) shifts in greenhouses. Rapid humidity drops dehydrate Corynespora cassiicola spores, inducing shrinkage, jerking movements, and weakened inter‐spore connections that drive detachment. Wind is essential for dispersal, with even mild airflow enabling rapid pathogen spread. These synergistic effects of
Jiayi Ma   +8 more
wiley   +1 more source

A MXene‐Based Nanothermal Knife Inhibits Aggresome‐Mediated Persister Formation for Preventing Dental Caries

open access: yesAdvanced Science, EarlyView.
Early childhood caries (ECC) involves cariogenic persisters that evade antimicrobial treatment. Persisters achieve this by downregulating heat shock proteins (HSPs) and formation of protein aggregates. Ti3C2 MXene‐based photothermal therapy (PTT) acts as a “nanothermal knife,” disrupting membranes, upregulating HSPs, inhibits aggregates, prevents ...
Yinyin Zhang   +8 more
wiley   +1 more source

EccDNA‐Driven VPS41 Amplification Alleviates Genotoxic Stress via Lysosomal KAI1 Degradation

open access: yesAdvanced Science, EarlyView.
Following ionizing radiation, eccDNA‐mediated VPS41 amplification slightly increases its expression but fails to prevent apoptosis. Introducing exogenous eccDNA or VPS41 enhances VPS41‐KAI1 interaction, promoting lysosomal degradation of KAI1. This process inhibits apoptotic signaling, enhancing cell survival and resistance to radiation‐induced damage.
Bin Shi   +12 more
wiley   +1 more source

Nephronectin (NPNT) is a Crucial Determinant of Idiopathic Pulmonary Fibrosis: Modulating Cellular Senescence via the ITGA3/YAP1 Signaling Axis

open access: yesAdvanced Science, EarlyView.
Through a comprehensive multi‐omics analysis, this study identifies a marked reduction in Nephronectin (NPNT) expression within fibrotic lung tissue. This reduction impairs the binding capability to the ITGA3 receptor, consequently causing YAP1 to persist in the cytoplasm, where it undergoes degradation.
Jiayu Guo   +20 more
wiley   +1 more source

Pain and Disability Therapy with Stabilization Exercises in Patients with Chronic Low Back Pain: A Meta-Analysis. [PDF]

open access: yesHealthcare (Basel)
Dimitrijević V   +5 more
europepmc   +1 more source

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