Results 71 to 80 of about 1,890,908 (315)

Central limit theorem for a birth-growth model with Poisson arrivals and random growth speed [PDF]

arXiv, 2021
We consider Gaussian approximation in a variant of the classical Johnson--Mehl birth-growth model with random growth speed. Seeds appear randomly in $\mathbb{R}^d$ at random times and start growing instantaneously in all directions with a random speed. The location, birth time and growth speed of the seeds are given by a Poisson process. Under suitable
arxiv  

Maternal smoking during pregnancy and early child outcomes [PDF]

, 2007
We estimate the harm from smoking during pregnancy upon child birth outcomes, using a rich dataset on a cohort of mothers and their births. We exploit a fixed effects approach to disentangle the correlation between smoking and birth weight from the ...
Tominey, Emma
core  

Cardiometabolic Health in Adults Born Premature With Extremely Low Birth Weight

Pediatrics, 2016
BACKGROUND: Young adults born with extreme prematurity have increased blood pressure and insulin resistance. This study documents their metabolic health as they enter their fourth decade of life.
K. Morrison, Laura Ramsingh, E. Gunn, D. Streiner, R. V. Van Lieshout, M. Boyle, H. Gerstein, L. Schmidt, S. Saigal   +8 more
semanticscholar   +1 more source

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

Molecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park, Jae Won Oh, Hyewon Chung, Jung Won Kwon, Yi Rang Na, Kwang Pyo Kim, Seung Hyeok Seok   +6 more
wiley   +1 more source

Relationship between periodontal disease and preterm low birth weight: systematic review

The Pan African Medical Journal, 2016
Introduction Periodontal disease is a neglected bacterial infection that causes destruction of the periodontium in pregnant women. Yet its impact on the occurrence of adverse pregnancy outcomes has not systematically evaluated and there is no clear ...
Amare Teshome, A. Yitayeh
semanticscholar   +1 more source

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan, Elizabeth Thomas, Mehari M. Weldemariam, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang, Nicholas Ambulos, Bi‐Dar Wang, David Weber, Vincent C. O. Njar   +10 more
wiley   +1 more source

Monotone function estimation in the presence of extreme data coarsening: Analysis of preeclampsia and birth weight in urban Uganda [PDF]

arXiv, 2019
This paper proposes a Bayesian hierarchical model to characterize the relationship between birth weight and maternal pre-eclampsia across gestation at a large maternity hospital in urban Uganda. Key scientific questions we investigate include: 1) how pre-eclampsia compares to other maternal-fetal covariates as a predictor of birth weight; and 2 ...
arxiv  

Type 2 Diabetes Risk Alleles Are Associated With Reduced Size at Birth [PDF]

, 2009
OBJECTIVE: Low birth weight is associated with an increased risk of type 2 diabetes. The mechanisms underlying this association are unknown and may represent intrauterine programming or two phenotypes of one genotype.
A. J. Bennett, A. Pouta, A. Ruokonen, A. T. Hattersley, B. Shields, Babenko, Bernstein, C. J. Groves, C. M. Lindgren, C. Power, D. P. Strachan, Davey Smith, E. Hypponen, E. Zeggini, Edghill, Frayling, Freathy, G. D. Smith, Gluckman, Godfrey, Golding, Grunnet, H. Lango, Hattersley, Hattersley, Higgins, Hypponen, J. R.B. Perry, Knight, Lindsay, M. I. McCarthy, M. N. Weedon, M.-R. Jarvelin, N. J. Timpson, P. Elliott, Pearson, R. M. Freathy, Rantakallio, S. M. Ring, Sladek, Steinthorsdottir, T. M. Frayling, Weedon   +42 more
core   +2 more sources

Meta-Analysis of Neurobehavioral Outcomes in Very Preterm and/or Very Low Birth Weight Children

Pediatrics, 2009
OBJECTIVE: Sequelae of academic underachievement, behavioral problems, and poor executive function (EF) have been extensively reported for very preterm (≤33 weeks' gestation) and/or very low birth weight (VLBW) (≤1500 g) children.
Cornelieke S H Aarnoudse‐Moens, N. Weisglas‐Kuperus, J. V. van Goudoever, J. Oosterlaan   +3 more
semanticscholar   +1 more source

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

Molecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu, Jianchao Wang, Fuqing Chen, Xuefeng Wang, Bin Lan, Ruyi Fu, Hong Wen, Fangfang Chen, Wei Hong, Tian‐Yu Tang, Ying He, Gang Chen, Jianyin Zhou, Hai‐Long Piao, Di Chen, Shu‐Yong Lin   +15 more
wiley   +1 more source