Results 131 to 140 of about 6,553,946 (302)
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Low flows : mechanisms, forecasts and climate change impacts [PDF]
, 2013 A research on low flows may seem controversial for a “wet” country protected by dykes and barriers. However, low flows in dry summers such as in 1976, 1985 and 2003 indicate that it may happen also in the Rhine basin. Improved medium-range and seasonal low fow forecasts are important as there is an increasing interest to account for low flow forecasts ...
openaire +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Exploring Seasonality Indices for Low-Flow Analysis on Tibagi Watershed (Brazil)
HydrologyThis study investigated the seasonality of low-flow discharges in the Tibagi watershed, Paraná, Brazil, through the analysis of three indices: Seasonality Ratio (SR), Seasonality Index (SI), and Seasonality Histogram (SH).
Alexandre Sokoloski de Azevedo Delduque de Macedo +1 more
doaj +1 more source
The occasional low-flow priapism
Canadian Journal of Rural Medicine, 2020 Andrew, Baker +2 more
openaire +2 more sources
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
No flow during low-flow cardiopulmonary bypass
The Journal of Thoracic and Cardiovascular Surgery, 1991 R H, Taylor +2 more
openaire +2 more sources
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source