Results 41 to 50 of about 9,368,117 (260)

Seismic site characterization at the western Cephalonia Island in the aftermath of the 2014 earthquake series

open access: yesInternational Journal of Geo-Engineering, 2017
Background The site response during a strong earthquake event may be proven crucial for earthquake hazard assessment and risk mitigation. Two moderate magnitude earthquakes that occurred in early 2014 in Cephalonia produced the largest ground motion ...
I. Kassaras   +3 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Kernel Density Estimation: a novel tool for visualising training intensity distribution in biathlon

open access: yesFrontiers in Sports and Active Living
PurposeThis study introduces two-dimensional (2D) Kernel Density Estimation (KDE) plots as a novel tool for visualising Training Intensity Distribution (TID) in biathlon. The goal was to assess how KDE plots, alongside traditional training metrics, might
Craig A. Staunton   +7 more
doaj   +1 more source

Calculation of the wave parameters for sea dyke design and upgrading

open access: yesVietnam Journal of Mechanics, 2008
Sea dyke system is the effective mean for protecting the coastal low-lying areas from storm attack (the most dangerous storm induced phenomena are storm wave and surges).
Nguyen Manh Hung   +2 more
doaj   +1 more source

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

Performance analysis for pseudo-random asynchronous FH-CDMA system based on average-hit method

open access: yesDianxin kexue, 2016
The pseudo-random M-ary sequence (such as RS code,polynomial code and low-hit zone FH code and so forth) is widely adopted as FH code in FH-CDMA system.However,the performance of FH-CDMA system employing FH sequence is usually evaluated by simulation,and
GTao ZHEN, Qi ZENG
doaj   +2 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

Shoreline Change Analysis of Amini Island, Lakshadweep Using Remote Sensing and GIS [PDF]

open access: yesISPRS Annals of the Photogrammetry, Remote Sensing and Spatial Information Sciences
Lakshadweep Islands, a chain of low-lying coral atolls located in Arabian Sea, are among the most climate sensitive regions of India. Its airport and residential areas are predicted to be affected by sea level rise.
D. Mhalaskar, R. Panchang
doaj   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

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