Jianxin Liu,1,* Tingting Shang,1,* Fengjuan Wang,1 Yang Cao,1 Lan Hao,1 JianLi Ren,1,2 Haitao Ran,1,2 Zhigang Wang,1,2 Pan Li,1,2 Zhiyu Du3 1Chongqing Key Laboratory of Ultrasound Molecular Imaging, 2Department of Ultrasound, 3Postgraduate Department ...
Liu J +9 more
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This review article highlights the historical developments and current state of knowledge of an important neuromodulation technology: low-intensity focused ultrasound.
Morgan N. Collins, Karen A. Mesce
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Empirical limitations of current low-intensity focused ultrasound simulation platforms
Background: Transcranial low-intensity focused ultrasound (LIFU) is an emerging tool for noninvasive neuromodulation, with potential therapeutic applications across a range of neuropsychiatric disorders. As the field advances toward clinical translation,
Sierra D. Brandts +7 more
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Medial prefrontal cortex-targeted low-intensity focused ultrasound alleviates migraine-related allodynia and affective symptoms via modulating glutamate/GABA balance in mice [PDF]
Background Migraine affects nearly one billion people worldwide and remains a major global health burden with inadequate treatment options. In this study, transcranial low-intensity focused ultrasound (LIFU) targeting the medial prefrontal cortex (mPFC ...
Jiayi Liu +17 more
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A pilot clinical study of low-intensity transcranial focused ultrasound in Alzheimer’s disease [PDF]
Purpose Increasing attention has been paid to low-intensity transcranial focused ultrasound (tFUS) for its potential therapeutic effects in Alzheimer's disease (AD). While preclinical studies have shown promising therapeutic effects of low-intensity tFUS
Hyeonseok Jeong +7 more
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LIFU (Low-Intensity Focused Ultrasound) Activated Tumor-Starvation/Oxidative-Stress Combined Therapy for Treating Retinoblastoma [PDF]
Luya Quan,1– 3 Mengzhu Wang,2 Zhigang Wang,2 Zhiyu Du3 1Department of Ophthalmology, The Guizhou Provincial People’s Hospital, Guiyang, Guizhou, 550002, People’s Republic of China; 2Department of Ultrasound, Chongqing Key Laboratory of Ultrasound ...
Quan L, Wang M, Wang Z, Du Z
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Maoping Li,1,2 Hua Luo,3 Weiyang Zhang,1 Kunyan He,4 Yong Chen,3 Jianxin Liu,2 Junchen Chen,5 Dong Wang,1 Lan Hao,2 Haitao Ran,2 Yuanyi Zheng,2 Zhigang Wang,2 Pan Li2 1Department of Ultrasound, The First Affiliated Hospital, Chongqing Medical University,
Li M +12 more
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Modulating nociception networks: the impact of low-intensity focused ultrasound on thalamocortical connectivity. [PDF]
Abstract Pain engages multiple brain networks, with the thalamus serving as a critical subcortical hub. This study aims to explore the effects of low-intensity transcranial focused ultrasound-induced suppression on the organization of thalamocortical nociceptive networks. We employed MR-guided focused ultrasound, a potential non-invasive
Mishra A +12 more
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Low-intensity focused ultrasound to the posterior insula reduces temporal summation of pain [PDF]
Background: The insula and dorsal anterior cingulate cortex (dACC) are core brain regions involved in pain processing and central sensitization, a shared mechanism across various chronic pain conditions.
Alexander In +3 more
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Focused ultrasound for treatment of peripheral brain tumors [PDF]
Malignant brain tumors are the leading cause of cancer-related death in children and remain a significant cause of morbidity and mortality throughout all demographics.
Phillip Mitchell Johansen +5 more
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