Results 241 to 250 of about 127,255 (282)

Low-Intensity Focused Ultrasound Produces Immune Response in Pancreatic Cancer

Ultrasound in Medicine & Biology, 2022
Pancreatic adenocarcinoma is an aggressive malignancy with limited therapeutic treatments available and a 5-y survival less than 10%. Pancreatic cancers have been found to be immunogenically "cold" with a largely immunosuppressive tumor microenvironment. There is emerging evidence that focused ultrasound can induce changes in the tumor microenvironment
Jordan B, Joiner, Nancy P, Kren, Phillip G, Durham, Autumn J, McRee, Paul A, Dayton, Yuliya, Pylayeva-Gupta   +5 more
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Low Intensity Focused Ultrasound Modulation of Vincristine Induced Neuropathy

Neuroscience, 2020
Previously, we showed internal low intensity focused ultrasound (liFUS) improves nociceptive thresholds in rats with vincristine-induced neuropathy (VIN) for 48-h post-treatment. Here, we perform more rigorous behavioral testing with the internal device and introduce external liFUS treatment.
Abigail, Hellman, Teresa, Maietta, Kanakaharini, Byraju, Yunseo, Linda Park, Miriam, Shao, Andrea, Liss, Paul, Neubauer, Clif, Burdette, Goutam, Ghoshal, Jiang, Qian, Julia, Nalwalk, Julie G, Pilitsis   +11 more
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Low Intensity Focused Ultrasound Modulation of Neural Circuits Activity

2019 IEEE 6th Portuguese Meeting on Bioengineering (ENBENG), 2019
Ultrasound neuromodulation (UNMOD) has gained popularity as a new state-of-the-art technique for the research and treatment of neurological and psychiatric illnesses. Ultrasounds (US) can be transmitted in a noninvasive manner to deep-brain regions with a focus of a few millimeters in size.
Machado, Francisca, Magalhâes, Ricardo, Mendes, P. M., Sousa, Nuno   +3 more
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Preliminary study on Low Intensity Focused Ultrasound system For neuromodulation

2017 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 2017
A Prototype Low Intensity Focused Ultrasound for brain targeting in a rat model was developed and tested. Accordingly, were evaluated low intensity focused ultrasound accuracy and performance. By utilizing the Rat Brain, no death or necrosis of cells, it was confirmed that the energy is gathered at that targeted.
, Ju Hyung Lee, , Hyun Ki Hong, , Byeong-Wook Song, , Yu Jin Jung, , Young Cheol Na, , Nam Hyun Kim, , Bong-Soo Kim   +6 more
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Progress in Noninvasive Low-Intensity Focused Ultrasound Neuromodulation

Stroke
Low-intensity focused ultrasound represents groundbreaking medical advancements, characterized by its noninvasive feature, safety, precision, and broad neuromodulatory capabilities. This technology operates through mechanisms, for example, acoustic radiation force, cavitation, and thermal effects.
Jinru Feng, Zixiao Li
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Low-intensity focused ultrasound-augmented Cascade chemodynamic therapy via boosting ROS generation

Biomaterials, 2021
Fenton reaction-mediated chemodynamic therapy (CDT), which destroys tumor cells by converting H2O2 into cytotoxic hydroxyl radical (OH) and singlet oxygen (1O2) species, is a promising field. However, Fenton-based CDT is severely impaired by the inappropriate tumor environment associated with undesirable intratumoral acidity and insufficient H2O2 ...
Liming Deng, Mingzhu Liu, Danli Sheng, Yuanli Luo, Dong Wang, Xian Yu, Zhigang Wang, Haitao Ran, Pan Li   +8 more
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Beamforming Design for High-Resolution Low-Intensity Focused Ultrasound Neuromodulation

ICASSP 2020 - 2020 IEEE International Conference on Acoustics, Speech and Signal Processing (ICASSP), 2020
Low-intensity focused ultrasound (LIFU) has been shown to modulate neural activity. Recent experiments suggest potential applications of LIFU stimulation for treating neuropsychiatric disorders like depression and Alzheimer’s. The modulation effect is usually positively correlated with the ultrasound intensity, and there exists a minimum intensity ...
Boqiang Fan, Wayne Goodman, Raymond Y. Cho, Sameer A. Sheth, Richard R. Bouchard, Behnaam Aazhang   +5 more
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Effects of low-intensity focused ultrasound on the mouse submandibular gland

Ultrasound in Medicine & Biology, 2006
Ultrasound is expected to make a considerable contribution to drug delivery systems (DDSs). We tested the hypothesis that low-intensity focused ultrasound (LIFU) increases vessel permeability in the mouse submandibular gland without causing parenchymal damage.
Jun, Shuto, Issei, Ichimiya, Masashi, Suzuki   +2 more
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Low Intensity Transcranial Focused Ultrasound in Patients with PTSD

2023
We are investigating the feasibility of using transcranial focused ultrasound of the amygdala to change amygdala activity and psychophysiological arousal in patients with posttraumatic stress disorder (PTSD). We will also investigate if changes in amygdala activity will correspond with changes in PTSD symptoms.
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