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A Prototype Stimulator System for Noninvasive Low Intensity Focused Ultrasound Delivery
2012A prototype Low Intensity Focused Ultrasound (LIFU) stimulator system was developed to evaluate non-invasive neuromodulation in a large animal model. We conducted a feasibility study on a Göttingen minipig, demonstrating reversible, targeted transcranial neuromodulation. The hypothalamus of the minipig was repeatedly stimulated with LIFU which
Amit P, Mulgaonkar +9 more
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Influence of Skull Anisotropic Mechanical Properties in Low-Intensity Focused Ultrasound
Journal of Computational Acoustics, 2016Low-intensity focused ultrasound (LIFU) is a new noninvasive brain stimulation technique where ultrasound is applied with low frequency and intensity to focus at a target region within the brain in order to exhibit or inhibit neuronal activity. In applying LIFU to the human brain, the skull is the main barrier due to its well-known high anisotropic ...
Mohamed K. Metwally +5 more
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Repeated neuromodulation with low-intensity focused ultrasound in patients with Alzheimer's disease
Journal of Alzheimer’s DiseaseBackground Low-intensity focused ultrasound (LIFU), a non-invasive targeted brain stimulation technology, has shown promise for therapeutic applications in Alzheimer's disease (AD) patients. Despite its potential, the implications of repeated LIFU neuromodulation in AD patients remain to be investigated.
Hyeonseok Jeong +9 more
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Cerebellar Inhibition Using Low-Intensity Focused Ultrasound (229)
Neurology, 2020Jean-Francois Nankoo +5 more
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Current treatment and future directions in the management of anal cancer
Ca-A Cancer Journal for Clinicians, 2022Leila T Tchelebi +2 more
exaly
Low-intensity focused ultrasound for human neuromodulation
Nature Reviews Methods PrimersWynn Legon, Andrew Strohman
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Management of glioblastoma: State of the art and future directions
Ca-A Cancer Journal for Clinicians, 2020Aaron Tan, David M Ashley, Giselle Lopez
exaly
Ultrasound Microsystems for minimally-invasive neuromodulation via low-intensity focused ultrasound
Proceedings of the MATSUS Fall 2023 Conference, 2023openaire +1 more source
Low-Intensity Focused Ultrasound: An Intervention for Fentanyl Addiction Relapse
Fentanyl use disorder (FUD) drives a persistent public health crisis characterized by high overdose mortality, polysubstance use, and relapse rates >50% despite medications for opioid use disorder (MOUD). Although U.S. drug overdose deaths declined from >110,000 in 2022–2023 to ~80,000–85,000 in 2024, synthetic opioids including fentanyl remain ...openaire +1 more source

