Results 181 to 190 of about 3,184,733 (264)

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Compact, Low-Loss, High-Speed Graphene Hybrid Modulator

Leuthold J, Ma P, Zhang X, Heni W, Floery N, Blatter T, Horst Y, Watanabe T, Wang C, Wu T, Li B, Sun M, Wang Z, Keller K, Burla M, Emboras A, Novotny L, Elder D, Dalton L.   +18 more
europepmc   +1 more source

Preparation and Magnetic Properties of Low-Loss Soft Magnetic Composites Using MgO-Phenolic Resin Coating. [PDF]

Materials (Basel)
Wan L, Sun X, Li J, Wu S.
europepmc   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

Investigation of hybrid plasmons in a highly crystalline Bi₂Se₃/C₆₀ heterostructure using low-loss electron energy loss spectroscopy. [PDF]

Commun Mater
McCauley M, Ansari L, Gity F, Rogers M, Burton J, Sasaki S, Ramasse Q, Knox C, Hurley PK, MacLaren D, Moorsom T.   +10 more
europepmc   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Ultracompact Programmable Silicon Photonics Using Layers of Low-Loss Phase-Change Material Sb₂Se₃ of Increasing Thickness. [PDF]

ACS Photonics
Blundell S, Radford TW, Ajia IA, Lawson D, Yan X, Banakar M, Thomson DJ, Zeimpekis I, Muskens OL.   +8 more
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Two CMOS Wilkinson Power Dividers Using High Slow-Wave and Low-Loss Transmission Lines. [PDF]

Micromachines (Basel)
Pakasiri C, Teng WS, Wang S.
europepmc   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source