Results 191 to 200 of about 17,065,072 (359)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Relationship Between Skeletal Muscle Mass Indexes and Muscular Function, Metabolic Profile and Bone Mineral Density in Women with Recommendation for Bariatric Surgery

Diabetes, Metabolic Syndrome and Obesity, 2019
Nara Nóbrega Crispim Carvalho,1,2 Vinícius José Baccin Martins,3 João Modesto Filho,2 Francisco Bandeira,4 Flávia Cristina Fernandes Pimenta,5 José Luiz de Brito Alves1 1Department of Nutrition, Health Sciences ...
Crispim Carvalho NN, Baccin Martins VJ, Modesto Filho J, Bandeira F, Fernandes Pimenta FC, de Brito Alves JL   +5 more
doaj  

Low mass dilepton production at ultrarelativistic energies

, 2008
Elena Bratkovskaya, W. Cassing, O. Linnyk   +2 more
openalex   +1 more source

Low‐level Determination of Residual Methyl Methane Sulfonate and Ethyl Methane Sulfonate in Pharmaceuticals by Gas Chromatography with Mass Spectrometry [PDF]

, 2009
M Sarat, M. Ramakrishna, Y. Suresh, S. Harikrishna, C. Rambabu, K. Kishore, K. Nagabhushana Reddy   +6 more
openalex   +1 more source

Voltage Rollercoaster Filtering of Low-Mass Contaminants During Native Protein Analysis. [PDF]

J Am Soc Mass Spectrom, 2020
McGee JP, Melani RD, Goodwin M, McAlister G, Huguet R, Senko MW, Compton PD, Kelleher NL.   +7 more
europepmc   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

A low-mass planet candidate orbiting Proxima Centauri at a distance of 1.5 AU. [PDF]

Sci Adv, 2020
Damasso M, Del Sordo F, Anglada-Escudé G, Giacobbe P, Sozzetti A, Morbidelli A, Pojmanski G, Barbato D, Butler RP, Jones HRA, Hambsch FJ, Jenkins JS, López-González MJ, Morales N, Peña Rojas PA, Rodríguez-López C, Rodríguez E, Amado PJ, Amado PJ, Anglada G, Feng F, Gómez JF.   +21 more
europepmc   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Optimizing High-Resolution Mass Spectrometry for the Identification of Low-Abundance Post-Translational Modifications of Intact Proteins

, 2017
Lisa E. Kilpatrick, Eric L. Kilpatrick
openalex   +2 more sources

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source