Results 241 to 250 of about 17,065,072 (359)

Low-mass-ion discriminant equation (LOME) for ovarian cancer screening. [PDF]

BioData Min, 2016
Lee JH, Yoo BC, Kim YH, Ahn SA, Yeo SG, Cho JY, Kim KH, Kim SC.   +7 more
europepmc   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

SIDM on FIRE: hydrodynamical self-interacting dark matter simulations of low-mass dwarf galaxies. [PDF]

Mon Not R Astron Soc, 2017
Robles VH, Bullock JS, Elbert OD, Fitts A, González-Samaniego A, Boylan-Kolchin M, Hopkins PF, Faucher-Giguère CA, Kereš D, Hayward CC.   +9 more
europepmc   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

On the existence of low-mass dark matter and its direct detection. [PDF]

Sci Rep, 2015
Bateman J, McHardy I, Merle A, Morris TR, Ulbricht H.   +4 more
europepmc   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Evidence from stable isotopes and ¹⁰Be for solar system formation triggered by a low-mass supernova. [PDF]

Nat Commun, 2016
Banerjee P, Qian YZ, Heger A, Haxton WC.
europepmc   +1 more source

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

The ALMA-PILS survey: First detections of ethylene oxide, acetone and propanal toward the low-mass protostar IRAS 16293-2422 [PDF]

, 2016
J. M. Lykke, A. Coutens, J. K. Jørgensen, M. H. D. van der Wiel, R. T. Garrod, H. S. P. Müller, P. Bjerkeli, Tyler L. Bourke, H. Calcutt, M. N. Drozdovskaya, Cécile Favre, Edith C. Fayolle, S. K. Jacobsen, Karin I. Öberg, M. V. Persson, E. F. van Dishoeck, S. F. Wampfler   +16 more
openalex   +1 more source

TREX-DM: a low-background Micromegas-based TPC for low-mass WIMP detection. [PDF]

Eur Phys J C Part Fields, 2016
Iguaz FJ, Garza JG, Aznar F, Castel JF, Cebrián S, Dafni T, García JA, Irastorza IG, Lagraba A, Luzón G, Peiró A.   +10 more
europepmc   +1 more source