ABSTRACTObjectiveCerebrospinal fluid (CSF) orexin‐A has been suggested to be a biomarker of Alzheimer disease (AD). In both cognitively unimpaired healthy older adults and individuals with symptomatic AD, CSF orexin‐A is positively associated with CSF Aβ42, p‐tau181, and total tau (t‐tau) concentrations.
Ruijin Lu+13 more
wiley +1 more source
A predictive nomogram based on triglyceride glucose index to body mass index ratio for low appendicular skeletal muscle mass. [PDF]
Zou J+7 more
europepmc +1 more source
ABSTRACTCavin‐4 was identified as a potential autoantigen for immune‐mediated rippling muscle disease (iRMD). To validate this, we developed and tested various immunoassays, including a cell‐based assay (CBA), cavin‐4 recombinant protein ELISA, and multi‐peptide ELISA. Among 19 iRMD patients, all exhibited muscle rippling, and 13 had percussion‐induced
Reghann G. LaFrance‐Corey+13 more
wiley +1 more source
APCI-Multistage Mass Spectrometry Following Liquid Chromatography for Selected 4-Desmethyl-Sterols and Their Deuterium-Labelled Analogues Unveils Characteristic Fragmentation Routes for Cholesterol and Phytosterols Identification. [PDF]
Cinquepalmi V+4 more
europepmc +1 more source
ABSTRACT Objective Certain frontotemporal lobar degeneration subtypes, including TDP‐A and B, can either occur sporadically or in association with specific genetic mutations. It is uncertain whether syndromic or imaging features previously associated with these patient groups are subtype or genotype specific.
Sean Coulborn+17 more
wiley +1 more source
Impact of sarcopenia on gait independence in older orthopaedic patients: a comparison of 2 diagnostic algorithms. [PDF]
Ikemoto T+7 more
europepmc +1 more source
Early BMI Change, Cognitive Decline, and CSF AD Biomarkers Alterations in Parkinson's Disease
ABSTRACT Objective To examine the relationship of early BMI change with subsequent cognitive decline, CSF AD biomarkers alterations, and progression to dementia in patients with PD. Methods Study data were prospectively collected from the PPMI cohort. Weight/height data at enrollment and second‐year clinical visit were utilized to calculate BMI change.
Rui Zhong, Kezhong Zhang
wiley +1 more source
Quantitative evaluation of muscle mass based on chest high-resolution CT and its prognostic value for tuberculosis: a retrospective study. [PDF]
Huang A+4 more
europepmc +1 more source
Damage mechanism and evolution model of geopolymer stabilized coarse grained fillings subjected to repeated freeze-thaw actions. [PDF]
Wang S+5 more
europepmc +1 more source
Evaluation of Waist-Calf Circumference Ratio to Assess Sarcopenia in Older Patients with Chronic Low Back Pain: A Retrospective Observational Study. [PDF]
Kim HJ, Kim JY, Kim SH.
europepmc +1 more source