Results 81 to 90 of about 3,156,291 (263)
Mass Production of 2023 KMTNet Microlensing Planets. I. Low Mass Ratio
The Astronomical JournalWe initiate the systematic search for planets in the 2023 data of the Korea Microlensing Telescope Network (KMTNet), focusing on those planets found by the KMTNet AnomalyFinder with low preliminary estimates of the mass ratio, q
Yoon-Hyun Ryu +36 more
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Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Mass Transfer in Low Mass Close Binaries [PDF]
International Astronomical Union Colloquium, 1997 AbstractThe mass transfer process in low mass close binaries is reviewed. The driving mechanisms and the stability properties are discussed by means of general, simple formulations. A model in terms of mass transfer instabilities is suggested to explain the outbursts of GRO J1655–40 in 1994.
openaire +1 more source
The clinical eficacy of vitamin D in children with primary low bone mass [PDF]
Pediatric Endocrinology, Diabetes and Metabolism, 2011 Introduction: Vitamin D suplementation in prevention and treatment of osteoporosis is a widely accepted standard, but the latest studies show the necessity of increasing the intake of this vitamin to keep its concetration on higher levels ?
Danuta Chlebna-Sokół, Jolanta Karalus
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Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Health disparities and climate change in the Marshall Islands
Annals of MedicineThe small island nations, territories, and states dotting the Pacific are among the most disproportionately affected populations worldwide in the face of climate change.
Kathryn J. Pollard +7 more
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Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source