Results 131 to 140 of about 14,850,784 (326)

Real‐World Performance of CSF Kappa Free Light Chains in the 2024 McDonald Criteria

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Kappa free light chains (KFLCs) in the cerebrospinal fluid (CSF) have a similar performance to CSF‐restricted oligoclonal bands (OCB) for multiple sclerosis (MS) diagnosis. To help with implementation, we set out to resolve several remaining uncertainties: (1) performance in a real‐world cohort and the 2024 McDonald criteria; (2 ...
Maya M. Leibowitz, Ryan Cooper, Stefania Kaninia, Kathryn I. Challis, Will Greenway, Maria Bonello, Mahmoud Elbahnasawi, Deborah T. Shode, Dominika Gajdasik, Victor Iliev, Alison M. E. Whitelegg, Ian Galea   +11 more
wiley   +1 more source

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito, Chiara Meneghini, Alice Galli, Luca Gallo, Pierfrancesco Mitrotti, Paola Dimartino, Marianna Inglese, Cinzia Zatti, Alessandro Lupini, Andrea Pilotto, Alessandro Padovani, Micol Avenali, Enza Maria Valente, Cristina Tassorelli, Silvia P. Caminiti   +14 more
wiley   +1 more source

Ultralow-Noise Chopper Amplifier for Seafloor E-Field Measurement

Sensors
The seafloor E-field signal is extremely weak and difficult to measured, even with a high signal-to-noise ratio. The preamplifier for electrodes is a key technology for ocean-bottom electromagnetic receivers.
Sixuan Song, Kai Chen
doaj   +1 more source

Brainstem and Cerebellar Volume Loss and Associated Clinical Features in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Progressive Supranuclear Palsy (PSP) is a neurodegenerative ‘tauopathy’ with predominating pathology in the basal ganglia and midbrain. Caudal tau spread frequently implicates the cerebellum; however, the pattern of atrophy remains equivocal.
Chloe Spiegel, Timothy P. Siejka, Cassandra Marotta, Josh J. Y. Lee, Kelly Bertram, Terence J. O'Brien, Meng Law, Lucy Vivash, Ian H. Harding   +8 more
wiley   +1 more source

A solid-state low-noise preamplifier [PDF]

Solid state low noise preamplifier for particle detector of electrostatic accelerator ...
Hansen, D. O., Roy, N. L.
core   +1 more source

Noise Characterization and Filtering in the MicroBooNE Liquid Argon TPC

, 2017
The low-noise operation of readout electronics in a liquid argon time projection chamber (LArTPC) is critical to properly extract the distribution of ionization charge deposited on the wire planes of the TPC, especially for the induction planes.
Acciarri, R., Adams, C., An, R., Anthony, J., Asaadi, J., Auger, M., Bagby, L., Balasubramanian, S., Baller, B., Barnes, C., Barr, G., Bass, M., Bay, F., Bishai, M., Blake, A., Bolton, T., Bullard, B., Caicedo, D. A. Martinez, Camilleri, L., Caratelli, D., Carls, B., Cavanna, F., Chen, H., Church, E., Cianci, D., Cohen, E., Collin, G. H., Conrad, J. M., Convery, M., Crespo-Anadon, J. I., De Geronimo, G., de Vries, J. Jan, Del Tutto, M., Devitt, D., Dytman, S., Eberly, B., Ereditato, A., Esquivel, J., Fadeeva, A. A., Fernandez, R. Castillo, Fleming, B. T., Foreman, W., Furmanski, A. P., Garcia-Gamez, D., Garvey, G. T., Genty, V., Goeldi, D., Gollapinni, S., Graf, N., Gramellini, E., Greenlee, H., Grosso, R., Guenette, R., Hackenburg, A., Hamilton, P., Hen, O., Hewes, J., Hill, C., Ho, J., Horton-Smith, G., Hourlier, A., Huang, E. -C., James, C., Jen, C. -M., Jiang, L., John, J. St., Johnson, R. A., Joshi, J., Jostlein, H., Kaleko, D., Karagiorgi, G., Ketchum, W., Kirby, B., Kirby, M., Kobilarcik, T., Kreslo, I., Laube, A., Li, S., Li, Y., Lister, A., Littlejohn, B. R., Lockwitz, S., Lorca, D., Louis, W. C., Luethi, M., Lundberg, B., Luo, X., Marchionni, A., Mariani, C., Marshall, J., Meddage, V., Miceli, T., MicroBooNE collaboration, Mills, G. B., Moon, J., Mooney, M., Moore, C. D., Mousseau, J., Murrells, R., Naples, D., Nienaber, P., Nowak, J., Palamara, O., Paolone, V., Papavassiliou, V., Pate, S. F., Pavlovic, Z., Piasetzky, E., Porzio, D., Pulliam, G., Qian, X., Raaf, J. L., Radeka, V., Rafique, A., Rescia, S., Rochester, L., Russell, B., Sanchez, L. Escudero, Schmitz, D. W., Schukraft, A., Seligman, W., Shaevitz, M. H., Sinclair, J., Smith, A., Snider, E. L., Soderberg, M., Soldner-Rembold, S., Soleti, S. R., Spentzouris, P., Spitz, J., Strauss, T., Szelc, A. M., Tagg, N., Terao, K., Thomson, M., Thorn, C., Toups, M., Tsai, Y. -T., Tufanli, S., Usher, T., Van De Pontseele, W., Van de Water, R. G., Viren, B., von Rohr, C. Rudolf, Weber, M., Wickremasinghe, D. A., Wolbers, S., Wongjirad, T., Woodruff, K., Yang, T., Yates, L., Yu, B., Zeller, G. P., Zennamo, J., Zhang, C.   +154 more
core   +1 more source

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

Feasibility and Tolerability of Performing Portable MRI for Neurological Disorders in an Outpatient Neurology Clinic: A Prospective Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Accessing brain magnetic resonance imaging (MRI) can be challenging, especially for underserved patients, which may lead to disparities in neurological diagnosis. Method This mixed‐methods study enrolled adults with one of four neurological disorders: mild cognitive impairment or dementia of the Alzheimer type, multiple sclerosis ...
Maya L. Mastick, Nomin Enkhtsetseg, Joseph Sadok, Matheus Mochetti, Annabel Sorby Adams, Jennifer Guo, Cristina Trapaga Hacker, Isabella Gomez Hjerthen, Seungwon Lee, Siddharth Satish, Andrew S. Ham, Justin Hill, Denis Balaban, Kevin Kyle, Rebecca L. Gillani, Marcelo Matiello, Aleksandar Videnovic, Eric C. Klawiter, W. Taylor Kimberly, Farrah J. Mateen   +19 more
wiley   +1 more source

A New Way for Effective Reducing Brake Temperature and Noise of Brake Pad

机车电传动, 2015
With the theoretical analysis of friction brake temperature and brake noise, and adjusting formulation and process, a new type of microporous composite brake pad was developed successfully, which had a microporous structure to effectively reduce friction
JIN Jiansheng, YANG Yang, NIU Lianjie, FAN Mengzhen, ZHANG Dingquan   +4 more
doaj  

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source