Results 91 to 100 of about 9,744,465 (303)

Low-Noise 3-D Avalanche Photodiodes

IEEE Photonics Journal, 2016
In this paper, we present a new 3-D structure for the InP-based avalanche photodiode, aiming at decreasing the excess noise factor. To the best of our knowledge, it is the first time new device designs based on the recently developed 3-D spatial dead ...
Zhiwei Wu, Jingshu Guo, Yuan Li, Yanli Zhao   +3 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Compact conversion and cyclostationary noise modelling of pn junction diodes in low-injection - Part II: Discussion [PDF]

, 2004
Starting from the compact conversion and cyclostationary pn diode noise model presented in the companion paper, we present an extensive validation based on comparisons with physics-based numerical simulations.
Bonani, Fabrizio, Ghione, Giovanni, Donati Guerrieri, Simona   +2 more
core   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

A 6.7 μW Low-Noise, Compact PLL with an Input MEMS-Based Reference Oscillator Featuring a High-Resolution Dead/Blind Zone-Free PFD

Sensors
This article reports a 110.2 MHz ultra-low-power phase-locked loop (PLL) for MEMS timing/frequency reference oscillator applications. It utilizes a 6.89 MHz MEMS-based oscillator as an input reference.
Ahmed Kira, Mohannad Y. Elsayed, Karim Allidina, Vamsy P. Chodavarapu, Mourad N. El-Gamal   +4 more
doaj   +1 more source

Characterization of low noise technologies applied to a Fullscale fuselage mounted nose landing gear

, 2015
The negative impact of aircraft noise includes effects on population's health, land use planning and economic issues such as building restrictions and operating restrictions for airports. Thus, the reduction of noise generated by aircraft at take-off and
Esposito, Marco,, Dahan, Jeremy, Bianco, Antonello, Bennett, Gareth J.,, O'Reilly, Ciarán,, Amoroso, Francesco,, AMOROSO, FRANCESCO, O'Reilly, Ciaran, Esposito, Marco, Kennedy, John, Kennedy, John,, Dahan, Jeremy,, Bruno, Massimiliano, Di Giulio, Massimiliano,, Neri, Eleonora, Neri, Eleonora,, Di Giulio, Massimiliano, Bianco, Antonello,, Bruno, Massimiliano,, Bennett, Gareth J.   +19 more
core   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

EMD-based filtering (EMDF) of low-frequency noise for speech enhancement [PDF]

, 2012
An Empirical Mode Decomposition based filtering (EMDF) approach is presented as a post-processing stage for speech enhancement. This method is particularly effective in low frequency noise environments.
Soraghan, John J., Chatlani, Navin
core   +2 more sources

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source