Results 41 to 50 of about 709,749 (262)
A low noise CMOS camera system for 2D resonant inelastic soft X-ray scattering
Frontiers in Physics, 2023 Resonant Inelastic X-ray Scattering (RIXS) is a powerful spectroscopic technique to study quantum properties of materials in the bulk. A novel variant of RIXS, called 2D RIXS, enables concurrent measurement of the scattered X-ray spectrum for a wide ...
Nord Andresen +8 more
doaj +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Journal of Research of the National Bureau of Standards, 1987 We describe the design, schematics, and performance of a very low noise FET cascode input amplifier. This amplifier has noise performance of less than [Formula: see text] and 0.25 [Formula: see text] over the 500 Hz to 50 kHz frequency range. The amplifier is presently being used in conjunction with a Penning ion trap but is applicable to a wide ...
Jefferts, Steven R., Walls, F. L.
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Noise-optimized ultrastable low-noise current amplifier [PDF]
Review of Scientific Instruments, 2019 We have developed a noise-optimized ultrastable low-noise current amplifier (ULCA) aimed at reducing the uncertainty at low currents. It involves a thin-film resistor network with 6.75 GΩ at the high-ohmic path which reduces the noise level to 1.6 fA/Hz. Noise investigations as well as short-term and long-term stability studies were carried out.
C. Krause +3 more
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Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Low-discrepancy blue noise sampling [PDF]
ACM Transactions on Graphics, 2016 We present a novel technique that produces two-dimensional low-discrepancy (LD) blue noise point sets for sampling. Using one-dimensional binary van der Corput sequences, we construct two-dimensional LD point sets, and rearrange them to match a target spectral profile while preserving their low discrepancy.
Abdalla G. M. Ahmed +7 more
openaire +3 more sources
A Two-Step A/D Conversion and Column Self-Calibration Technique for Low Noise CMOS Image Sensors
Sensors, 2014 In this paper, a 120 frames per second (fps) low noise CMOS Image Sensor (CIS) based on a Two-Step Single Slope ADC (TS SS ADC) and column self-calibration technique is proposed.
Jaeyoung Bae +4 more
doaj +1 more source
A low‐noise current‐reused CMOS active inductor by exploiting Gm‐boosting technique
IET Microwaves, Antennas & Propagation, 2021 This work introduces a new low‐noise current‐reused CMOS active inductor (AI) based on Gyrator‐C configuration. In the proposed AI, a simple common‐source amplifier is utilised for boosting effective Gm and improving noise performance of the AI.
Abdollah Sabbaghi, Emad Ebrahimi
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Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source