Results 81 to 90 of about 7,783,593 (306)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Multichip packaging with thermal insulation [PDF]
, 1968 Thermal insulation technique permits low and high power electronic chips to operate in the same package without thermal cross-coupling. An alumina glass shield thermally isolates the low power chip from the high power chip while Kovar substrate acts as a
Mc Inturff, R. G., Mend, W. G.
core +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Low-power ring counter drives high-level loads [PDF]
, 1966 Ring counter dissipates very low power in standby conditions, yet drives high-current loads on a low duty-factor basis. Complementary transistors are used so that in one selected stage both transistors are conducting while the transistors of the other ...
core +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Low Power Superconducting Microwave Applications and Microwave Microscopy [PDF]
, 1998 We briefly review some non-accelerator high-frequency applications of superconductors. These include the use of high-Tc superconductors in front-end band-pass filters in cellular telephone base stations, the High Temperature Superconductor Space ...
Anlage, Steven M. +6 more
core +2 more sources
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
A Study on the Evolution of Flow Regime in a Gas-Assisted Submerged High-Pressure Water Jet
FluidsHigh-pressure water jet technology is widely utilized for cleaning marine artificial structures due to its portability, efficiency, and environmental friendliness, yet traditional jets underperform in submerged environments.
Hao Yan +3 more
doaj +1 more source
Low power arcjet performance [PDF]
An experimental investigation was performed to evaluate arc jet operation at low power. A standard, 1 kW, constricted arc jet was run using nozzles with three different constrictor diameters.
Curran, Francis M. +1 more
core +1 more source