Results 51 to 60 of about 433,421 (301)

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Reducing Power Dissipation in SRAM during Test

open access: yes, 2006
In this paper we analyze the power consumption of SRAM memories and demonstrate that the full functional pre-charge activity is not necessary during test because of the predictable addressing sequence.
Girard, Patrick   +4 more
core   +1 more source

Low-Power Consumption Design and Optimization of New Artificial Anal Sphincter

open access: yesShanghai Jiaotong Daxue xuebao, 2021
Based on the hardware of the new artificial anal sphincter system, this paper analyzes the power consumption of each module. After low-power consumption design and reasonable setting of the sampling period, the system power consumption is significantly ...
YAO Shengjian, YAN Guozheng, WANG Zhiwu, ZHOU Zerun, JIANG Pingping, DING Zifan, HUA Fangfang, ZHAO Kai, HAN Ding
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Soft Error-Aware Design Optimization of Low Power and Time-Constrained Embedded Systems [PDF]

open access: yes, 2010
In this paper, we present the first study that examines the impact of application task mapping on the reliability of multiprocessor system-on-chip (MPSoC) in the presence of single-event upsets (SEUs).
Rishad A Shafik   +5 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Low-power and high-fanout bus design techniques [PDF]

open access: yes, 2014
Low-power techniques pose an important concern, when designing autonomous electronic devices. Most of the upcoming applications increasingly demand high performance and low-power consumption.
Rodriguez Ramos, Alejandro
core  

Low power and low voltage CMOS digital circuit techniques

open access: yes, 1998
One of many important factors affecting power consumption is the choice of circuit technique for logic, latches and flip-flops. We analyze the power consumption at circuit level and use the results to guide the choice of circuit technique.
Svensson, Christer,   +3 more
core   +1 more source

2.45 GHz Power and Data Transmission for a Low-Power Autonomous Sensors Platform [PDF]

open access: yes, 2004
This paper describes a power conversion and data recovery system for a microwave powered sensor platform. A patch microwave antenna, a matching filter and a rectifier make the system front-end and implement the RF-to-DC conversion of power carrier.
Jin Liu   +9 more
core   +1 more source

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