Results 141 to 150 of about 2,410,220 (312)
Low vapor pressure solvents for single-molecule junction measurements
Non-polar solvents commonly used in scanning tunneling microscope-based break junction measurements exhibit hazards and relatively low boiling points (b.p.) that limit the scope of solution experiments at elevated temperatures.
Zelin, Miao +9 more
core +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
IEEE AccessPower cables, one of the key components of electric power systems (EPS) in future wide-body all-electric aircraft (AEA), have a lot of room for improvement in achieving low system mass leading to high power density designs.
Anoy Saha, Mona Ghassemi
doaj +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
IEEE Transactions on Neural Systems and Rehabilitation EngineeringWearing robotic gloves has become increasingly crucial for hand rehabilitation in stroke patients. However, traditional robotic gloves can exert additional pressure on the hand, such as prolonged use leading to poor blood circulation and muscle stiffness.
Jinxu Yu +5 more
doaj +1 more source
Low pressure pneumatic servomechanisms [PDF]
, 2013 Tests on a continuous action low pressure electro-pneumatic linear motion servomechanism are described. Data from individual tests on the components of this system, including the servo valve and the actuator, is used for analogue computer simulations. The simulations are shown to model the experimental system over a wide range of conditions.
openaire +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Importance of pulse pressure at low systolic blood pressure [PDF]
European Heart Journal, 2021 Franz H Messerli +3 more
openaire +2 more sources