Directed evolution of enzymes at the crossroads of tradition and innovation
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Quantification and Evaluation of Low-Pressure Nitrogen Sorption Hysteresis in Marine-Terrestrial Shale Reservoirs. [PDF]
Hu J +6 more
europepmc +1 more source
Evaluation of CO2 solubility in potential aqueous amine-based solvents at low CO2 partial pressure
Prachi Singh +2 more
openalex +2 more sources
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef +2 more
wiley +1 more source
Corrections to "Study of Hemp Fiber Properties Modified via Long-Duration Low-Pressure Argon and Oxygen Plasma Treatments". [PDF]
Bapat K +4 more
europepmc +1 more source
Fabrication and Testing of a Low-cost Foot Pressure Sensing System
Jasim Ahmed Ali AL-Baghdadi +2 more
openalex +2 more sources
Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source
Manganese Volatilization and Its Influence on Low-Pressure Carburizing Process Effects. [PDF]
Atraszkiewicz R, Zgórniak P.
europepmc +1 more source
In situ studies on palladium/rutile titanium dioxide exposed to low pressure hydrogen gas environments [PDF]
Marian David Bongers
openalex +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source

