Results 51 to 60 of about 934,200 (296)

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Satellite Camera CCD Read-out System Design, Based on Noise Optimization with Respect to Satellite Limitations [PDF]

فصلنامه علوم و فناوری فضایی, 2010
Satellite camera Charged Coupled Device (CCD) read out system needs a high Signal to Noise Ratio (SNR). This is because of the special and inevitable space imaging payload noises. These noises include CCD noises, satellite noises such as lack of complete
H. Bazrafshan, Sh. Baradaran Shokouhi, B. Ghorbani Vagheii   +2 more
doaj  

Optomechanical reference accelerometer

, 2015
We present an optomechanical accelerometer with high dynamic range, high bandwidth and read-out noise levels below 8 ${\mu}$g/$\sqrt{\mathrm{Hz}}$. The straightforward assembly and low cost of our device make it a prime candidate for on-site reference ...
Cervantes, Felipe Guzman, Gerberding, Oliver, Melcher, John, Pratt, Jon R., Taylor, Jacob M.   +4 more
core   +1 more source

SFE16, a low noise front-end integrated circuit dedicated to the read-out of large Micromegas detectors [PDF]

IEEE Transactions on Nuclear Science, 2000
A front-end BiCMOS ASIC was specially developed for the Micromegas detectors to be used in the Small Angle Tracker of the COMPASS experiment at CERN. Each of the 16 channels of this integrated circuit contains a low noise preamplifier with a 100 ns peaking time filter and a discriminator driving a low-level differential digital buffer.
E. Delagnes, P. Abbon, Y. Bedfer, J.C. Faivre, F. Kunne, A. Magnon, S. Platchkov, P. Rebourgerad, D. Thers   +8 more
openaire   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Design and Analysis of a Resistive Sensor Interface With Phase Noise-Energy-Resolution Scalability for a Time-Based Resistance-to-Digital Converter

Frontiers in Electronics, 2022
This article presents the design and analysis of a resistive sensor interface with three different designs of phase noise-energy-resolution scalability in time-based resistance-to-digital converters (RDCs), including test chip implementations and ...
Dong-Hyun Seo, Baibhab Chatterjee, Sean M. Scott, Daniel J. Valentino, Dimitrios Peroulis, Shreyas Sen   +5 more
doaj   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Determining Conversion Gain and Read Noise Using a Photon-Counting Histogram Method for Deep Sub-Electron Read Noise Image Sensors

IEEE Journal of the Electron Devices Society, 2016
A new method for characterizing deep sub-electron read noise image sensors is reported. This method, based on the photon-counting histogram, can provide easy, independent and simultaneous measurements of the quanta exposure, conversion gain, and read ...
Dakota A. Starkey, Eric R. Fossum
doaj   +1 more source

Printable Organic PIN Phototransistor and Its Application for Low Power and Noise Imaging Detection

IEEE Photonics Journal, 2022
The power consumption and the opto-electric noise of organic photo-detectors are the challenges for large-scale detecting and imaging applications to surpass.
Zhi Tao, Haixin lin, Yanqing Zhu, Die Hu, Weiguang Yang, Jiangyong Pan, Xiang Liu   +6 more
doaj   +1 more source

Development of frequency domain multiplexing for the X-ray Integral Field Unit (X-IFU) on the Athena

, 2016
We are developing the frequency domain multiplexing (FDM) read-out of transition-edge sensor (TES) microcalorimeters for the X-ray Integral Field Unit (X-IFU) instrument on board of the future European X-Ray observatory Athena.
Adams, Joseph S., Akamatsu, Hiroki, Bandler, Simon R., Bruijn, Marcel P., Chervenak, James A., de Vries, Cor P., Gottardi, Luciano, Jackson, Brian D., Kilbourne, Caroline A, Kiviranta, Mikko, Linden, A. J. van den, Ravensberg, Kevin, Smith, Stephen J., van der Kuur, Jan   +13 more
core   +1 more source