Results 101 to 110 of about 11,043,311 (307)

MicroRNA‐941 Acts as a Novel Prognostic Predictor and Oncogenic Driver in Colorectal Cancer

Annals of Gastroenterological Surgery, EarlyView.
Upregulation of miR‐941 was a promising diagnostic and prognostic biomarker for CRC patients. Inhibition of miR‐941 significantly suppressed CRC cellular events and triggered ferroptosis. The oncogenic functions of miR‐941 were mediated through targeting TRPS1.
Hong Li, Yang Liu, Hua Chen, Jialin Li, Xinchun Li, Yanmin Chen   +5 more
wiley   +1 more source

Low anterior rectal resection; the impact of anastomotic fistula on incidence and severity of low anterior resection syndrome

Journal of Mind and Medical Sciences
Objectives. Low anterior resection is a common surgical procedure for rectal cancer, but it is associated with a distressing complication known as Low Anterior Resection Syndrome (LARS).
Giorgiana Coțofană Graure, Cecil Mirea, Silviu Daniel Preda, Ștefan Pătrașcu, Tiberiu Stefanita Tenea-Cojan, Adina Turcu-Stiolica, Alexandru Munteanu, Vlad Padureanu, Dragos Margaritescu, Sandu Ramboiu, Dan Cartu, Valeriu Șurlin, Petre Radu   +12 more
doaj   +1 more source

Evolution and hot topics of laparoscopic sphincter-preserving surgery for low rectal cancer [PDF]

Waike lilun yu shijian
Rectal cancer is a prevalent malignant tumor both in China and worldwide. Despite the availability of numerous sphincter-preserving procedures for low rectal cancer, each with specific indications, advantages, and limitations, no single procedure ...
ZHI Yihao, ZHAO Xuan, ZHENG Minhua
doaj   +1 more source

Current Status and Challenges of Imaging‐Based Diagnosis of Lymph Node Metastasis in Colon Cancer: The Lymph Node Committee of the Japanese Society for Cancer of the Colon and Rectum

Annals of Gastroenterological Surgery, EarlyView.
This review of the status and challenges of diagnosis of lymph node metastasis in colon cancer suggests that it is currently difficult to establish strict criteria for lymph node metastasis, indicating only moderate diagnostic performance. ABSTRACT Background Accurate pre‐treatment evaluation of lymph node metastasis (LNM) in colon cancer is important ...
Shimpei Ogawa, Yuji Takayama, Yasuyuki Takamizawa, Yukihide Kanemitsu, Hideki Ueno   +4 more
wiley   +1 more source

Functional results of intersphincteric resection for low rectal cancer

British Journal of Surgery, 2007
Abstract Background Intersphincteric resection (ISR) is the ultimate sphincter-preserving operation for very low rectal cancer. The aim of this study was to assess defaecatory function after ISR in relation to the degree of resection of the internal anal sphincter.
K, Yamada, S, Ogata, Y, Saiki, M, Fukunaga, Y, Tsuji, M, Takano   +5 more
openaire   +2 more sources

Multiparametric MRI in rectal cancer [PDF]

, 2019
MRI has a pivotal role in both pretreatment staging and posttreatment evaluation of rectal cancer. The accuracy of MRI in pretreatment staging is higher compared with posttreatment evaluation.
Emre Balık, Bengi Gürses, Medine Böge, Emre Altınmakas   +3 more
core   +1 more source

Carcinoembryonic Antigen Messenger RNA in Pelvic Lavage Fluid Predicts Local Recurrence After Curative‐Intent Resection of Rectal Cancer

Annals of Gastroenterological Surgery, EarlyView.
Pelvic lavage carcinoembryonic antigen (CEA) mRNA was quantified in 178 patients undergoing curative‐intent resection for rectal cancer. Positive pelvic lavage CEA mRNA was significantly associated with local recurrence and provided additional prognostic information beyond circumferential resection margin (CRM) status.
Hiroyuki Asai, Yushi Yamakawa, Kazuyoshi Shiga, Shuhei Uehara, Akira Kato, Takuya Suzuki, Hajime Ushigome, Hiroki Takahashi, Yoichi Matsuo, Shuji Takiguchi   +9 more
wiley   +1 more source

Age‐Dependent Prognostic Significance of Preoperative Transthyretin After Curative Resection for Stage I–III Colorectal Cancer

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background Preoperative malnutrition and systemic inflammation are established determinants of adverse outcomes in colorectal cancer (CRC). Transthyretin (TTR), a rapid‐turnover hepatic protein, reflects both nutritional and inflammatory status; however, its clinical utility may be influenced by age‐ and sex‐related variability.
Ayane Kawata, Yuji Miyamoto, Hiro Nakamura, Takahiko Akiyama, Kota Arima, Katsuhiro Ogawa, Yukiharu Hiyoshi, Masaaki Iwatsuki   +7 more
wiley   +1 more source

Anastomotic leakage after laparoscopic total mesorectal excision for low rectal cancer

, 2011
Aim: Our single centre comparative study is focused on perioperative outcomes of laparoscopic total mesorectal excision in patients with middle and low rectal cancer with attention to complications of double stapling coloanal anastomosis with and without
Miloslav Duda, Renata Soumarova, Lukas Adamcik, Javed Parvez, Matej Skrovina, Roman Kycina, Jiri Bartos   +6 more
core  

The prognostic and therapeutic significance of biological molecular markers in human anorectal carcinomas treated with 5'fluorouracil chemoradiation. [PDF]

, 2005
Advances in tumour biology have led to studies of new biological markers, which may predict treatment response and clinical outcome independently of standard clinicopathological variables.
Mawdsley, S.K.V.
core