Results 41 to 50 of about 130,252 (262)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

A temperature control strategy to achieve low-temperature district heating in North China

International Journal of Sustainable Energy Planning and Management, 2020
The data includes historical actual operating data of a District Heating System (DHS) in Tianjin and weather forecast data. The DHS operating data, which includes supply and return temperature from February 16, 2018, to March 12, 2018, is collected from ...
Yin Bai
doaj   +1 more source

Simulation models and performance assessment of district heating substations [PDF]

, 2014
Development of new technologies and methodologies regarding district heating substation operational control strategies are increasingly found nowadays.
Himpe, Eline, Janssens, Arnold, Vaillant Rebollar, Julio   +2 more
core  

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Thermoeconomic approach for the analysis of low temperature district heating systems [PDF]

, 2012
In this paper a thermoeconomic analysis of district heating systems is performed. The analysis aims at comparing possible options to supply heat to the users, using low temperature networks.
Albana Kona, Verda, Vittorio
core  

Geothermal contribution to the energy mix of a heating network when using Aquifer Thermal Energy Storage: modeling and application to the Paris basin [PDF]

, 2013
International audienceAquifer Thermal Energy Storage (ATES) is a promising solution for reducing the time mismatch between energy production and demand in urban environments, and recent successful experiences suggest that technical issues can be overcome.
Cordier, Elisabeth, Goblet, Patrick, Hamm, Virginie, Lesueur, Hervé, Réveillère, Arnaud   +4 more
core   +2 more sources

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Classification through analytic hierarchy process of the barriers in the revamping of traditional district heating networks into low temperature district heating: an Italian case study

International Journal of Sustainable Energy Planning and Management, 2019
The revamping of existing high temperature district heating systems with low temperature solutions will ensure a better usage of primary energy thanks to the reduction of thermal losses through the networks and to the possibility of use low grade ...
Marco Pellegrini, Augusto Bianchini, Alessandro Guzzini, Cesare Saccani   +3 more
doaj   +1 more source

Building energy performance characterisation based on dynamic analysis and co-heating test [PDF]

, 2014
A demonstration zero-carbon neighborhood is being raised in the city of Kortrijk, Belgium in the framework of the ECO-Life project within the CONCERTO initiative.
Himpe, Eline, Janssens, Arnold, Vaillant Rebollar, Julio   +2 more
core   +1 more source

Thermoeconomics as a tool for the design and analysis of energy savings initiatives in buildings connected to district heating networks [PDF]

, 2012
District Heating (DH) is a rational way to supply heat to buildings in urban areas. This is expected to play an important role in future energy scenarios, mainly because of the possibility to recover waste heat and to integrate renewable energy sources ...
Kona Albana, Verda, Vittorio
core   +1 more source