Improving delivery of low tidal volume ventilation in 10 ICUs [PDF]
BMJ Open Quality, 2022 Low tidal volume ventilation (LTVV) is standard of care for mechanically ventilated patients with acute respiratory distress syndrome and has been shown to improve outcomes in the general mechanically ventilated population. Despite these improved outcomes, in clinical practice the LTVV standard of care is often not met.
Scott R Gunn +3 more
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The Effect of Low Tidal Volume Ventilation on Inflammatory Cytokines During Cardiopulmonary Bypass [PDF]
Brazilian Journal of Cardiovascular Surgery, 2021 Introduction: Halting ventilation during cardiopulmonary bypass (CPB) is implemented to operate in a less bleeding setting. It sustains a better visualization of the operation area and helps to perform the operation much more comfortably.
Nazım Kankılıç +2 more
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Implementing nudges to promote utilization of low tidal volume ventilation (INPUT): a stepped-wedge, hybrid type III trial of strategies to improve evidence-based mechanical ventilation management [PDF]
Implementation Science, 2021 Background Behavioral economic insights have yielded strategies to overcome implementation barriers. For example, default strategies and accountable justification strategies have improved adherence to best practices in clinical settings.
Meeta Prasad Kerlin +11 more
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Biotrauma during ultra-low tidal volume ventilation and venoarterial extracorporeal membrane oxygenation in cardiogenic shock: a randomized crossover clinical trial [PDF]
Annals of Intensive Care, 2021 Background Cardiogenic pulmonary oedema (CPE) may contribute to ventilator-associated lung injury (VALI) in patients with cardiogenic shock. The appropriate ventilatory strategy remains unclear.
Laura Amado-Rodríguez +12 more
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Efficacy of using tidal volume challenge to improve the reliability of pulse pressure variation reduced in low tidal volume ventilated critically ill patients with decreased respiratory system compliance [PDF]
BMC Anesthesiology, 2022 Background The prediction accuracy of pulse pressure variation (PPV) for fluid responsiveness was proposed to be unreliable in low tidal volume (Vt) ventilation.
Yujun Xu, Jun Guo, Qin Wu, Junjun Chen
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Hyaluronic acid plasma levels during high versus low tidal volume ventilation in a porcine sepsis model [PDF]
PeerJ, 2022 Background Shedding of the endothelial glycocalyx can be observed regularly during sepsis. Moreover, sepsis may be associated with acute respiratory distress syndrome (ARDS), which requires lung protective ventilation with the two cornerstones of ...
Rainer Thomas +9 more
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Organizational factors associated with adherence to low tidal volume ventilation: a secondary analysis of the CHECKLIST-ICU database [PDF]
Annals of Intensive Care, 2020 Background Survival benefit from low tidal volume (V T) ventilation (LTVV) has been demonstrated for patients with acute respiratory distress syndrome (ARDS), and patients not having ARDS could also benefit from this strategy.
Thais Dias Midega +10 more
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High vs. low tidal volume and pulmonary complications in patients with cervical spinal cord injury on mechanical ventilation: systematic review [PDF]
Frontiers in MedicineIntroductionCervical spinal cord injury (CSCI) patients on mechanical ventilation often lack standardized guidelines for optimal ventilatory support. This study reviews existing literature to compare outcomes between high tidal volume (HTV) and low tidal
Edinson Dante Meregildo-Rodríguez +5 more
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Low tidal volume ventilation. [PDF]
J Intensive Care Soc, 2018 Holden S, Nichani R.
europepmc +4 more sources
Journal of Anaesthesiology Clinical Pharmacology, 2019 Background and Aims: Ventilation can induce increase in inflammatory mediators that may contribute to systemic organ dysfunction. Ventilation-induced organ dysfunction is likely to be accentuated if there is a pre-existing systemic inflammatory response.
Vanya Chugh +6 more
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