Improving delivery of low tidal volume ventilation in 10 ICUs. [PDF]
Low tidal volume ventilation (LTVV) is standard of care for mechanically ventilated patients with acute respiratory distress syndrome and has been shown to improve outcomes in the general mechanically ventilated population. Despite these improved outcomes, in clinical practice the LTVV standard of care is often not met.
Donadee C +3 more
europepmc +5 more sources
Very low tidal volume ventilation with associated hypercapnia--effects on lung injury in a model for acute respiratory distress syndrome. [PDF]
BACKGROUND: Ventilation using low tidal volumes with permission of hypercapnia is recommended to protect the lung in acute respiratory distress syndrome. However, the most lung protective tidal volume in association with hypercapnia is unknown.
Hans Fuchs +4 more
doaj +4 more sources
The Effect of Low Tidal Volume Ventilation on Inflammatory Cytokines During Cardiopulmonary Bypass. [PDF]
Introduction: Halting ventilation during cardiopulmonary bypass (CPB) is implemented to operate in a less bleeding setting. It sustains a better visualization of the operation area and helps to perform the operation much more comfortably.
Kankılıç N, Aydın MS, Göz M.
europepmc +2 more sources
Nudging implementation of low tidal volume ventilation: a stepped wedge, cluster randomized trial. [PDF]
Background “Nudges” embedded in the electronic health record (EHR) facilitate desired decisions while preserving autonomy and may provide a scalable strategy to overcome the common implementation barrier of lack of knowledge about a best practice.
Kerlin MP +18 more
europepmc +2 more sources
Disparities Exist in the Application of Low Tidal-volume Ventilation in the Emergency Department. [PDF]
Low tidal-volume ventilation (LTVV), defined as a maximum tidal volume of 8 milliliters per kilogram (mL/kg) of ideal body weight, is a key component of lung protective ventilation. Although emergency department (ED) initiation of LTVV has been associated with improved outcomes, disparities in LTVV application exist.
Self M +7 more
europepmc +6 more sources
Hyaluronic acid plasma levels during high versus low tidal volume ventilation in a porcine sepsis model. [PDF]
Background Shedding of the endothelial glycocalyx can be observed regularly during sepsis. Moreover, sepsis may be associated with acute respiratory distress syndrome (ARDS), which requires lung protective ventilation with the two cornerstones of ...
Thomas R +9 more
europepmc +3 more sources
Organizational factors associated with adherence to low tidal volume ventilation: a secondary analysis of the CHECKLIST-ICU database. [PDF]
Background Survival benefit from low tidal volume (V T) ventilation (LTVV) has been demonstrated for patients with acute respiratory distress syndrome (ARDS), and patients not having ARDS could also benefit from this strategy.
Midega TD +10 more
europepmc +2 more sources
Efficacy of using tidal volume challenge to improve the reliability of pulse pressure variation reduced in low tidal volume ventilated critically ill patients with decreased respiratory system compliance. [PDF]
Background The prediction accuracy of pulse pressure variation (PPV) for fluid responsiveness was proposed to be unreliable in low tidal volume (Vt) ventilation.
Xu Y, Guo J, Wu Q, Chen J.
europepmc +2 more sources
Biotrauma during ultra-low tidal volume ventilation and venoarterial extracorporeal membrane oxygenation in cardiogenic shock: a randomized crossover clinical trial. [PDF]
Background Cardiogenic pulmonary oedema (CPE) may contribute to ventilator-associated lung injury (VALI) in patients with cardiogenic shock. The appropriate ventilatory strategy remains unclear.
Amado-Rodríguez L +13 more
europepmc +2 more sources
High vs. low tidal volume and pulmonary complications in patients with cervical spinal cord injury on mechanical ventilation: systematic review. [PDF]
IntroductionCervical spinal cord injury (CSCI) patients on mechanical ventilation often lack standardized guidelines for optimal ventilatory support. This study reviews existing literature to compare outcomes between high tidal volume (HTV) and low tidal
Meregildo-Rodríguez ED +5 more
europepmc +2 more sources

