Pancreatic ductal adenocarcinoma exhibits marked angiogenic and immune heterogeneity. We identified 28 angiogenesis‐associated immune genes and developed a seven‐gene AIGScore model comprising FGF2, ADGRB3, MMP2, TYMP, VASH1, VEGFD, and ITGAV. A high AIGScore was associated with poor survival, an immunosuppressive tumor microenvironment, and reduced ...
Qing Chang +4 more
wiley +1 more source
Management of primary blast lung injury: a comparison of airway pressure release versus low tidal volume ventilation. [PDF]
Scott TE +4 more
europepmc +1 more source
LINC00892 is lowly expressed in HCC. LINC00892 overexpression induces ribosomal stress via inhibiting SBDS, restrains EIF6 nuclear translocation and activates p53 pathway. LINC00892 overexpression and p53 activation jointly suppress HCC progression. High LINC00892 is associted with infiltration of CD8+ T cells, B cells and macrophages, and associated ...
Xu Zhang +6 more
wiley +1 more source
Comparison of limited driving pressure ventilation and low tidal volume strategies in adults with acute respiratory failure on mechanical ventilation: a randomized controlled trial. [PDF]
Tongyoo S +5 more
europepmc +1 more source
ABSTRACT With the approval of immunotherapies by regulatory bodies, head and neck squamous cell carcinoma (HNSCC) treatment has been revolutionized, and anti‐programmed cell death‐1 (anti‐PD‐1) agents are now the standard for platinum‐resistant recurrent/metastatic HNSCC.
Xiao‐Tong Yan +2 more
wiley +1 more source
Low Tidal Volume Ventilation Is Poorly Implemented for Patients in North American and United Kingdom ICUs Using Electronic Health Records. [PDF]
Samanta RJ +3 more
europepmc +1 more source
Mobile consumers influence the shoreward edge of intertidal seagrass ecosystems
Ecological paradigms suggest that the environmentally stressful edge of a habitat is determined by physical factors. The work finds that, counter to these paradigms, an environmentally stressful edge can also be impacted by biotic interactions and are more complex than suggested.
Stephanie R. Valdez +4 more
wiley +1 more source
‘Whitby Woman’, ‘Waitrose Woman’: Gender and Voting Behaviour at the 2024 UK General Election
Abstract Women were identified as key targets in the 2024 British general election. There was much speculation as to whether ‘Whitby’ or ‘Waitrose’ women would swing the result for Labour. This interest in women voters stemmed, at least partially, from the fact that the 2017 and 2019 British general elections were the first where a modern gender gap—a ...
Rosie Campbell +3 more
wiley +1 more source
Early pathophysiology-driven airway pressure release ventilation versus low tidal volume ventilation strategy for patients with moderate-severe ARDS: study protocol for a randomized, multicenter, controlled trial. [PDF]
Zhou Y +6 more
europepmc +1 more source

