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Chest, 1990
High airway pressure may be injurious to lung parenchyma, but lowering airway pressure using conventional mechanical ventilation necessitates lowering tidal volume (VT). Intubated patients in the surgical intensive care unit (SICU) were randomly assigned to group 1 (VT = 12 ml/kg, n = 56) or group 2 (VT = 6 ml/kg, n = 47).
P C, Lee +3 more
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High airway pressure may be injurious to lung parenchyma, but lowering airway pressure using conventional mechanical ventilation necessitates lowering tidal volume (VT). Intubated patients in the surgical intensive care unit (SICU) were randomly assigned to group 1 (VT = 12 ml/kg, n = 56) or group 2 (VT = 6 ml/kg, n = 47).
P C, Lee +3 more
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Low Tidal Volumes for Everyone?
Chest, 2019Since the first description of mechanical ventilation, our understanding of the positive and negative effects of this form of life support has continued to evolve. To maintain "normal" aeration of the lungs and "normal" blood gas measurements, patients often require much higher airway pressures and tidal volumes than would be expected in a healthy ...
Craig R, Rackley, Neil R, MacIntyre
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Low tidal volume ventilation in healthy dogs
Journal of Veterinary Emergency and Critical Care, 2012AbstractObjectiveTo determine if low tidal volume (VT) ventilation is associated with the development of respiratory acidosis and changes in lung function in healthy dogs.DesignRandomized prospective experimental cross‐over study.SettingPulmonary function laboratory at a university teaching hospital.AnimalsFive healthyBeagle dogs.InterventionsDogs were
Trisha, Oura +3 more
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Update on ARDS: Beyond the Low Tidal Volume
The American Journal of the Medical Sciences, 2009In 2000, the Acute Respiratory Distress Syndrome (ARDS) network1 published the results of a landmark trial in which a specific therapy was found to improve survival in patients with ARDS. This was the first trial to demonstrate an improvement in mortality since the original description of the syndrome over 30 years earlier.
Tarek A, Dernaika +2 more
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JAMA, 2012
lunginjurydevelopment(RR,0.33;95%CI,0.23-0.47),pulmonary infection (RR, 0.45; 95% CI, 0.22-0.92), and mortality (RR, 0.64; 95% CI, 0.46-0.89). Although these data seem compelling, several factors must be considered in their interpretation. A total of 15 randomized controlled trials were combined with 5 observational studies, but the observational ...
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lunginjurydevelopment(RR,0.33;95%CI,0.23-0.47),pulmonary infection (RR, 0.45; 95% CI, 0.22-0.92), and mortality (RR, 0.64; 95% CI, 0.46-0.89). Although these data seem compelling, several factors must be considered in their interpretation. A total of 15 randomized controlled trials were combined with 5 observational studies, but the observational ...
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The Journal of Pediatrics, 1980
Ten neonates with severe lung disease were studied while mechanically ventilated with standard volume preset infant ventilators, using two different ventilatory patterns. Slow ventilatory rates and high tidal volumes were alternated with rapid rates and low tidal volumes; minute ventilation, FIo2, PEEP, and I:E ratios were held constant.
S J, Boros, K, Campbell
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Ten neonates with severe lung disease were studied while mechanically ventilated with standard volume preset infant ventilators, using two different ventilatory patterns. Slow ventilatory rates and high tidal volumes were alternated with rapid rates and low tidal volumes; minute ventilation, FIo2, PEEP, and I:E ratios were held constant.
S J, Boros, K, Campbell
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Ventilation with a low tidal volume vs. an intermediate tidal volume during pleural decortication.
Annali italiani di chirurgia, 2022This study aims to evaluate the effects of low tidal volume and positive end expiratory pressure (PEEP) combined with pressure-controlled ventilation-volume guaranteed (PCV-VG) ventilation on one lung ventilation (OLV) in patients with tuberculous destroyed lung (TDL).Patients of two groups were all treated with volume controlled ventilation (VCV) on ...
Zhi Guo, Shi +4 more
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2019
Lung protective ventilation using 6 mL/kg of ideal body weight is the standard of practice in patients with acute respiratory distress syndrome (ARDS). The use of low tidal volume ventilation was associated with decreased morbidity and mortality in the ARMA trial [1].
J.-T. Chen, M. N. Gong
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Lung protective ventilation using 6 mL/kg of ideal body weight is the standard of practice in patients with acute respiratory distress syndrome (ARDS). The use of low tidal volume ventilation was associated with decreased morbidity and mortality in the ARMA trial [1].
J.-T. Chen, M. N. Gong
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1998
In the last 5 to 10 years, considerable attention has been paid to the ventilatory strategies used in the acute respiratory distress syndrome (ARDS) because ventilation could act not only as a symptomactic support but could also have an important impact on lung injury itself. Two general ideas are supporting this view.
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In the last 5 to 10 years, considerable attention has been paid to the ventilatory strategies used in the acute respiratory distress syndrome (ARDS) because ventilation could act not only as a symptomactic support but could also have an important impact on lung injury itself. Two general ideas are supporting this view.
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Low Tidal Volume Ventilation in Patients Without Acute Lung Injury
Cell Biochemistry and Biophysics, 2014Acute respiratory distress syndrome is a life threatening respiratory condition characterized by breakdown of the alveolar-capillary barrier, leading to flooding of the alveolar space producing the classical chest radiograph of bilateral pulmonary infiltrates.
Weibing, Tang +3 more
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