Results 51 to 60 of about 2,367,621 (266)

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Barriers to utilizing low vision devices among non-users with low vision: A cross-sectional study

The Rehabilitation Journal, 2023
Background: By recognizing and comprehending the obstacles that prevent low vision devices (LVDs) from being used effectively, the burden of blindness can be reduced.
Iqra Tariq, Fareeha Ayyub, Mehreen Tanveer, Shahid Iqbal, Arooshia Shahzadi   +4 more
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Insulin-Enhanced Biological Visual Rehabilitation in Neuroretinal Degeneration Patients Treated with Mesenchymal Cell-Derived Secretome

Pharmaceutics
Objectives: Insulin plays a crucial role in neuronal survival and oxidative stress modulation, making it a potential therapeutic target. This study investigates the effects of insulin in combination with a mesenchymal cell-derived secretome in patients ...
Paolo Giuseppe Limoli, Celeste Limoli, Marcella Nebbioso   +2 more
doaj   +1 more source

On-site forest fire smoke detection by low-power autonomous vision sensor [PDF]

, 2010
Early detection plays a crucial role to prevent forest fires from spreading. Wireless vision sensor networks deployed throughout high-risk areas can perform fine-grained surveillance and thereby very early detection and precise location of forest fires.
Cano Rojas, Alberto, Carmona Galán, Ricardo, Carranza González, Luis, Fernández Berni, Jorge, Martínez Carmona, Juan F., Morillas Castillo, Sergio, Rodríguez Vázquez, Ángel Benito   +6 more
core  

Exploiting the structure effectively and efficiently in low rank matrix recovery

, 2018
Low rank model arises from a wide range of applications, including machine learning, signal processing, computer algebra, computer vision, and imaging science.
Absil, Agarwal, Ahmed, Alter, Amelunxen, Beck, Blanchard, Blumensath, Boumal, Boyd, Bunk, Cai, Cai, Cai, Cai, Cai, Cai, Candes, Candes, Candes, Candes, Candes, Candès, Candès, Candès, Candès, Carmon, Chandrasekaran, Chen, Chen, Chen, Chen, Chen, Chen, Chen, Chen, Chen, Combettes, Davenport, Davenport, Ding, Donoho, Fazel, Ge, Ge, Ge, Goldberg, Gross, Hardt, Harrison, Huang, Jaggi, Jain, Jain, Ji, Jin, Keshavan, Kim, Kliesch, Koltchinskii, Krim, Kueng, Lanman, Li, Li, Lin, Ling, Ling, Liu, Liu, Lustig, Ma, Miao, Mishra, Mishra, Mishra, Mobahi, Mu, Negahban, Netrapalli, Ngo, Potter, Qu, Recht, Recht, Schermelleh, Srebro, Strohmer, Sun, Sun, Tanner, Tanner, Tao, Tharrault, Toh, Toh, Tomasi, Tu, Vandereycken, Wang, Wei, Wei, Wei, Wen, WenHuang, Xu, Yi, Zhang, Zhang, Zheng   +109 more
core   +2 more sources

A USB3.0 FPGA Event-based Filtering and Tracking Framework for Dynamic Vision Sensors [PDF]

, 2015
Dynamic vision sensors (DVS) are frame-free sensors with an asynchronous variable-rate output that is ideal for hard real-time dynamic vision applications under power and latency constraints.
Delbrück, T., Gómez Rodríguez, Francisco de Asís, Linares Barranco, Alejandro, Longinotti, L., Villanueva, V.   +4 more
core   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Psychosocial implications ofblindness and low-vision [PDF]

, 2007
This article discusses several aspects of psychosocial adjustment to blindness andlow-vision and proposes that the education of both the self and society are essential forpositive adjustment.
Schinazi, VR
core  

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon, Nathalie Picard, Valeria d'Andrea, Enchi Chang, Joseph Leffler, Eleonora Centofante, Matthew Taylor, Francesca Bardi, Francesca Cavicchiolo, Takao K. Hensch, Stefano Panzeri, Chinfei Chen, Michela Fagiolini   +12 more
wiley   +1 more source