Results 221 to 230 of about 11,848,296 (296)

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Efficient impedance source-based high voltage gain converter with smooth input current. [PDF]

Sci Rep
Hajilou M, Farzanehfard H.
europepmc   +1 more source

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

FEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav, Shweta Shweta, Manisha Malhotra, Vikash Maurya, Akhilesh Kumar   +4 more
wiley   +1 more source

A novel asymmetric thirteen level inverter for medium voltage applications. [PDF]

Sci Rep
Anil Kumar D, Prasanna L, Nayak Bhukya C, Vamsi Krishna P, Venkatesh PM, Arunyuvaraj K.   +5 more
europepmc   +1 more source

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

FEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima, Kotone Watanabe, Grigorii Sultanakhmetov, Aoi Fukuchi, Keiya Ito, Sawako Shimizu, Taro Saito, Akiko Asada, Kanae Ando   +8 more
wiley   +1 more source

A low component count high step up DC-DC converter using a coupled inductor. [PDF]

Sci Rep
Paşaoğlu A, Nadermohammadi A, Shams H, İran SP.   +3 more
europepmc   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Sub-Doppler rubidium atom cooling using a programmable agile integrated PZT-on-SiN resonator. [PDF]

Nat Commun
Isichenko A, Carpenter S, Montifiore N, Wang J, Dangi M, Chauhan N, Mukherjee P, Yang X, Indukuri N, Harrington MW, Zhong C, Kierzewski IM, Rudy RQ, Choy JT, Blumenthal DJ.   +14 more
europepmc   +1 more source

A High-Sensitivity MEMS Pressure Sensor with a Narrow Cross-Beam Membrane-Short Beam Structure. [PDF]

Micromachines (Basel)
Wang T, Xiao Z, Chen P, Nie M, Yan Z, Deng S, Chen J, Wang X, Liu J.   +8 more
europepmc   +1 more source

Beyond-Classical Ferroelectric Metamaterials: 3D-Printed Planar Lattices With Programmable Electro-Thermo-Mechanical Coupling. [PDF]

Adv Sci (Weinh)
Shi J, Ju K, Chen H, Orsat V, Sasmito AP, Ahmadi A, Akbarzadeh A.   +6 more
europepmc   +1 more source