Results 31 to 40 of about 13,537 (162)

Time‐Restricted Eating on Appetite and Inflammation in Adults With Obesity and Prediabetes: A Randomized Feeding Study

Obesity, EarlyView.
ABSTRACT Objective Time‐restricted eating (TRE) has gained attention for weight loss and cardiometabolic health improvement. The Time‐Restricted Intake of Meals (TRIM) study was a 12‐week randomized isocaloric and eucaloric feeding trial comparing 10‐h TRE to a 16‐h usual eating pattern (UEP) in adults with obesity and either prediabetes or diet ...
Daisy Duan, Susan Carnell, Scott J. Pilla, Stephanie T. Chung, Jeanne M. Clark, Nisa M. Maruthur   +5 more
wiley   +1 more source

‘We're not going to start lifting stones now…’: Stakeholder perspectives on the role of psychometric methods in outcome measurement

British Journal of Clinical Psychology, EarlyView.
Abstract Objectives Psychological outcome measures guide research and clinical decision‐making, yet many widely used tools were developed with limited psychometric rigour. Although advanced methods (e.g., item response theory, structural equation modelling) are now widely available, their added value in applied research remains uncertain and applied ...
David Byrne, Fiona Boland, Susan Brannick, Robert M. Carney, Pim Cuijpers, Alexandra L. Dima, Kenneth E. Freedland, Suzanne Guerin, David Hevey, Bishember Kathuria, Emma Wallace, Frank Doyle   +11 more
wiley   +1 more source

Performing Large‐Scale Genetic Analysis in the Bleeding Disorders Community

Haemophilia, EarlyView.
ABSTRACT Inherited bleeding disorders encompass a diverse group of conditions caused by genetic defects affecting coagulation factors, fibrinogen, von Willebrand factor, or platelet function. Despite major advances in quantitative and functional laboratory assays, a substantial diagnostic gap remains, particularly in patients with mild or atypical ...
Anna R. Blankstein, Sterre P. E. Willems, Saskia E. M. Schols, Rosanna Asselta, Gillian Lowe, Neil V. Morgan, Paula D. James   +6 more
wiley   +1 more source

Lowe Syndrome protein OCRL1 supports maturation of polarized epithelial cells.

PLoS ONE, 2011
Mutations in the inositol polyphosphate 5-phosphatase OCRL1 cause Lowe Syndrome, leading to cataracts, mental retardation and renal failure. We noted that cell types affected in Lowe Syndrome are highly polarized, and therefore we studied OCRL1 in ...
Adam G Grieve, Rachel D Daniels, Elena Sanchez-Heras, Matthew J Hayes, Stephen E Moss, Karl Matter, Martin Lowe, Timothy P Levine   +7 more
doaj   +1 more source

Profiles of autism characteristics in thirteen genetic syndromes: a machine learning approach

Molecular Autism, 2023
Background Phenotypic studies have identified distinct patterns of autistic characteristics in genetic syndromes associated with intellectual disability (ID), leading to diagnostic uncertainty and compromised access to autism-related support.
Natali Bozhilova, Alice Welham, Dawn Adams, Stacey Bissell, Hilgo Bruining, Hayley Crawford, Kate Eden, Lisa Nelson, Christopher Oliver, Laurie Powis, Caroline Richards, Jane Waite, Peter Watson, Hefin Rhys, Lucy Wilde, Kate Woodcock, Joanna Moss   +16 more
doaj   +1 more source

Caregiver sensitivity moderates effects of gestational inflammation on child ADHD symptoms

Journal of Child Psychology and Psychiatry, EarlyView.
Background Increased inflammation during pregnancy may increase the risk for child psychopathology, though prospective data remain preliminary. Child symptoms of attention‐deficit/hyperactivity disorder (ADHD) are particularly important due to ADHD's role as an early precursor of many later forms of externalizing and internalizing problems.
Elinor L. Sullivan, Jessica M. Tipsord, Elizabeth K. Nousen, Julia Williams, Sara Shao, Diana Vazquez Duque, Jennifer M. Loftis, Sarah L. Karalunas, Joel T. Nigg, Hanna C. Gustafsson   +9 more
wiley   +1 more source

LOWE SENDROMLU BİR OLGUNUN DAVRANIŞ FENOTİPİNE YAKLAŞIM

Cerrahpaşa Medical Journal, 2014
Background.­ The Lowe syndrome or oculocerebrorenal syndrome is a rare X linked recessive hereditary diseases which involves ocular defects, nervous system anomalies and renal dysfunction. The stubborness, temper tantrums and complex repetitive movements
Mehmet SEVEN, Zuhal SUYUGÜL, Adnan YÜKSEL, Seniha HACIHANEFİOĞLU, Ahmet AYDIN, Asım CENANİ   +5 more
doaj  

Case Report: Corneal Leucoma as a Novel Clinical Presentation of Nail-Patella Syndrome in a 5-Year-Old Girl

Frontiers in Pediatrics, 2021
Nail-patella syndrome (NPS) is a rare autosomal-dominant disorder characterized by the classic tetrad of absent or hypoplastic finger and toe nails, absent or hypoplastic patella, skeletal deformities involving the elbow joints, and iliac horns.
Ling Hou, Yue Du, Yubin Wu, Yue Zeng, Chengguang Zhao   +4 more
doaj   +1 more source

Innovative Field Applications of Probiotics, Prebiotics, and Medicinal Plant Products for Disease Control in Aquaculture

Journal of Fish Diseases, EarlyView.
ABSTRACT Disease outbreaks and the associated reliance on antibiotics pose major constraints to the sustainability of modern aquaculture. As regulatory pressures increase and consumer demand shifts toward residue‐free production, diverse biological interventions are gaining prominence as viable alternatives to chemotherapeutics.
Mustafa Öz, Enes Üstüner, Sümmani Çifci, Suat Dikel, Emin İleri, Furkan Budak   +5 more
wiley   +1 more source

Congenital Myopathy in Lowe Syndrome

Pediatric Neurology Briefs, 1990
Congeni tal fiber type disproportion myopathy is described in two brothers with oculo-cerebro-renal syndrome of Lowe from the Department of Pediatrics, Tsuchiura Kyoudou Hospital; Ibaraki; Tsukuba University; Tokyo Medical and Dental University; and ...
J Gordon Millichap
doaj   +1 more source