Results 131 to 140 of about 5,940,643 (309)
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Algorithms and literate programs for weighted low-rank approximation with missing data
Linear models identification from data with missing values is posed as a weighted low-rank approximation problem with weights related to the missing values equal to zero.
Markovsky, Ivan
core
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Operational characteristic and approximation performance analysis of Oustaloup fractance circuits
In this paper, we investigated operational characteristics and approximation performance of Oustaloup fractance rational approximation from a new perspective of fractional calculus operation.
LIU Pan-Pan, YUAN Xiao, TAO Lei, YI Zhou
doaj
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Interpolation of Multiparameter Approximation Spaces
We prove a general interpolation theorem for linear operators acting simultaneously in several approximation spaces which are defined by multiparametric approximation families.
Asekritova, Irina,, Brudnyi, Yuri,
core +1 more source
Existence and Approximation of Manifolds for the Swift-Hohenberg Equation with a Parameter
The existence and approximation of manifolds for the Swift-Hohenberg equation with a proper parameter have mainly been studied. Using the backward-forward systems from Swift-Hohenberg equation, the existence and specific representation forms of manifolds
Yanfeng Guo, Chunxiao Guo, Donglong Li
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source

