ABSTRACT The medical burdens of sickle cell disease (SCD) and transfusion‐dependent β‐thalassemia (TDT) are chronic and cumulative, even in children. Yet the effects expand beyond medications and healthcare visits due to their impacts on school attendance, academic performance, and peer engagement.
Mary Ann Etling +2 more
wiley +1 more source
Quantitative Global Survey Results of Acute Back Pain Sufferers Across Four Countries
Nadine Maybaum,1 Salvador Rios-Martinez,2 Martin Johnson3 1Haleon, Warren, NJ, USA; 2Internal Medicine Specialist Private Practice, Mexico City, Mexico; 3St Pancras Clinical Research, London, UKCorrespondence: Nadine Maybaum, Haleon, 184 Liberty Corner ...
Maybaum N, Rios-Martinez S, Johnson M
doaj
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Comparison of low back pain prevalence in adults between pre-pandemic and pandemic periods and related biopsychosocial aspects [PDF]
The global health crisis resulting from the outbreak of the coronavirus (SARS-CoV-2) has led to social distancing, the repercussions of which on physical and mental health are still being assessed.
Kerolyne Soares Mayer +2 more
doaj +1 more source
Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source
A systematic review and meta-synthesis of the impact of low back pain on people's lives [PDF]
Copyright @ 2014 Froud et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution,
Sue Patterson +24 more
core +2 more sources
Posisi Duduk dan Keluhan Nyeri Punggung Bawah Pada Kurir Pengantar Barang di Kota Tanjungpinang
Lower back pain is a sensation in the lower back refers to pain in the area between the lower ribs and above the legs, pain, and pain in the lower back resulting from injury or muscle tension, or it can also be caused by more specific conditions, such as
febe ferdianti natalia febe +2 more
doaj +1 more source
Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow +12 more
wiley +1 more source
Cell surface CD11c as a neutrophil aging marker molecule
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki +5 more
wiley +1 more source
Background. Lower back pain is one of the most common reasons people seek help from a physiotherapist. One of the techniques used in rehabilitation is resistance exercises with instability, such as exercises with TRX belts or on unstable planes.
Gabrielė Elijošiūtė +1 more
doaj +1 more source

