Results 171 to 180 of about 6,618,541 (298)

Cramer-Rao Lower Bound for SoOp-R-Based Root-Zone Soil Moisture Remote Sensing. [PDF]

IEEE J Sel Top Appl Earth Obs Remote Sens, 2020
Boyd DR, Gurbuz AC, Kurum M, Garrison JL, Nold BR, Piepmeier JR, Vega M, Bindlish R.   +7 more
europepmc   +1 more source

A lower bound on

Physics Letters B, 1983
John S. Hagelin, Frederick J. Gilman
openaire   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

On Applying Unit Propagation-Based Lower Bounds in Pseudo-Boolean Optimization

, 2008
Unit propagation-based (UP) lower bounds are used in the vast majority of current Max-SAT solvers. However, lower bounds based on UP have seldom been applied in Pseudo-Boolean Optimization (PBO) algorithms derived from the DPLL procedure for ...
Heras, Federico, Marques-Silva, Joao, Manquinho, Vasco, Vasco Manquinho, Joao Marques-silva, Federico Heras   +5 more
core  

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Near-Frustration-Free Electronic Structure Hamiltonian Representations and Lower-Bound Certificates. [PDF]

J Chem Theory Comput
Rubin NC, Low GH, DePrince Iii AE.
europepmc   +1 more source

Utility of In Vitro Bioactivity as a Lower Bound Estimate of In Vivo Adverse Effect Levels and in Risk-Based Prioritization. [PDF]

Toxicol Sci, 2020
Paul Friedman K, Gagne M, Loo LH, Karamertzanis P, Netzeva T, Sobanski T, Franzosa JA, Richard AM, Lougee RR, Gissi A, Lee JJ, Angrish M, Dorne JL, Foster S, Raffaele K, Bahadori T, Gwinn MR, Lambert J, Whelan M, Rasenberg M, Barton-Maclaren T, Thomas RS.   +21 more
europepmc   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Approximate Cramér-Rao lower bound analyses for semi-optimal energy thresholds selection in photon counting CT. [PDF]

Med Phys
Lee O.
europepmc   +1 more source