Results 181 to 190 of about 1,003,788 (328)

Bounding the A-hat genus using scalar curvature lower bounds and isoperimetric constants [PDF]

Q. M. Ma, Jinmin Wang, Guoliang Yu, Bo Zhu   +3 more
openalex   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

A New Theorem for Lower Bounds in NP-Hard Multi-Objective Scheduling Problems

Hasan Mahmood, Ayad M. Ramadan
openalex   +2 more sources

Lower bounds for multicolor van der Waerden numbers [PDF]

Zach Hunter
openalex   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Recent lower bounds for geometric-arithmetic index [PDF]

Discrete Mathematics Letters, 2019
Ana Portilla, Jose M. Rodrıguez, Jose M. Sigarreta   +2 more
doaj  

Lower bounds on trees and unicyclic graphs with respect to the misbalance rodeg index. [PDF]

Heliyon
Dehgardi N, Azari M, Shang Y.
europepmc   +1 more source

Lower bounds for genera of fiber products [PDF]

Fedor Pakovich
openalex   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Two New Families of Local Asymptotically Minimax Lower Bounds in Parameter Estimation. [PDF]

Entropy (Basel)
Merhav N.
europepmc   +1 more source