Results 91 to 100 of about 22,833 (219)

Role of differentially expressed microRNA-139-5p in the regulation of phenotypic internal anal sphincter smooth muscle tone. [PDF]

, 2017
The present study focused on the role of microRNA-139-5p (miRNA-139-5p) in the regulation of basal tone in internal anal sphincter (IAS). Applying genome-wide miRNA microarrays on the phenotypically distinct smooth muscle cells (SMCs) within the rat ...
Addya, Sankar, An, Steven S., Mee Yong, Hwan, Mohanty, Ipsita, Penn, Raymond B., Philllips, Benjamin, Rattan, Satish, Singh, Jagmohan   +7 more
core   +2 more sources

Utility of the Endoscopic Pressure Study Integrated System in Identifying Silent Gastroesophageal Reflux Disease During Routine Health Check‐ups

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Objectives The endoscopic pressure study integrated system (EPSIS) is a novel functional endoscopic modality that records intragastric pressure (IGP) waveforms during CO2 insufflation to evaluate lower esophageal sphincter (LES) function and diagnose gastroesophageal reflux disease (GERD).
Yohei Nishikawa, Haruhiro Inoue, Kazuki Yamamoto, Tomona Sakurai, Yukiko Okada, Kei Ushikubo, Kohei Shigeta, Ippei Tanaka, Satoshi Abiko, Mayo Tanabe, Takayoshi Ito, Noboru Yokoyama, Naoyuki Uragami   +12 more
wiley   +1 more source

Correlation of esophageal pressure-flow analysis findings with bolus transit patterns on videofluoroscopy [PDF]

, 2016
This is a pre-copyedited, author-produced version of an article accepted for publication in Diseases of the Esophagus following peer review. The version of record Omari TI, Szczesniak MM, Maclean J, Myers JC, Rommel N, Cock C and Cook IJ.
Cock, Charles, Cook, Ian James, Maclean, Julia C F, Myers, Jennifer C, Omari, Taher, Rommel, Nathalie, Szczesniak, Michal Marcin   +6 more
core   +1 more source

Major Basic Protein Deposition Without Eosinophilic Infiltration in Hypercontractile Esophagus: A Case Report

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Hypercontractile esophagus is a motility disorder characterized by excessive contractions in the esophageal body. Certain cases of hypercontractile esophagus exhibit eosinophilic infiltration in the muscle layer; however, its clinical significance is unclear.
Tetsuya Tatsuta, Keinosuke Hizuka, Shigeharu Ueki, Masatoshi Kaizuka, Shinji Oota, Keisuke Hasui, Hidezumi Kikuchi, Hiroto Hiraga, Daisuke Chinda, Hirotake Sakuraba   +9 more
wiley   +1 more source

Presence of GABAB Receptors Forming Heterodimers With GABAB1 and GABAB2 Subunits in Human Lower Esophageal Sphincter

Journal of Pharmacological Sciences, 2009
Baclofen, a GABAB-receptor (GABABR) agonist has been proposed to be useful as therapeutic agent for the management of gastro-esophageal reflux disease, but whether the compound acts directly at the lower esophageal sphincter (LES) remains to be ...
Yasuhiro Torashima, Yasuhito Uezono, Masato Kanaide, Yuko Ando, Akihito Enjoji, Takashi Kanematsu, Kohtaro Taniyama   +6 more
doaj   +1 more source

Dietary guideline adherence for gastroesophageal reflux disease. [PDF]

, 2014
BackgroundGastroesophageal reflux disease (GERD) is the most common gastrointestinal disease, and the cost of health care and lost productivity due to GERD is extremely high.
Block, Gladys, Buffler, Patricia, Corley, Douglas A, Kubo, Ai, Quesenberry, Charles P   +4 more
core   +2 more sources

Evaluating the Additional Value of Endoscopic Ultrasonography for Depth Assessment of Esophagogastric Junction Adenocarcinoma

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Objectives Endoscopic ultrasonography (EUS) is sometimes used to assess the depth of invasion in esophagogastric junction adenocarcinoma (EGJA); however, its diagnostic performance in EGJA remains unclear. This study aimed to evaluate the additional value of EUS to conventional endoscopy (CE) in assessing invasion depth. Methods In this single‐
Keita Suzuki, Yohei Ikenoyama, Ken Namikawa, Yoshitaka Tokai, Shoichi Yoshimizu, Yusuke Horiuchi, Akiyoshi Ishiyama, Toshiyuki Yoshio, Toshiaki Hirasawa, Manabu Takamatsu, Takahisa Matsuda, Junko Fujisaki   +11 more
wiley   +1 more source

Characterization of Esophageal Physiology Using Mechanical State Analysis [PDF]

, 2016
This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution and reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the ...
Cock, Charles, Costa, Marcello, Dinning, Phillip, Leibbrandt, Richard Eduard, Omari, Taher, Rommel, Nathalie, Tack, Jan, van Beckevoort, Dirk, Wang, Guangsong, Wiklendt, Lukasz   +9 more
core   +2 more sources

Is Single‐Session Peroral Endoscopic Myotomy With Fundoplication Safe and Effective in Achalasia? A Systematic Review and Meta‐Analysis

DEN Open, Volume 6, Issue 1, April 2026.
This meta‐analysis of nine studies (202 patients) demonstrates that peroral endoscopic myotomy with fundoplication (POEM‐F) achieves a technical success of 94.8% and significant symptom improvement (Eckardt score reduction from 8.3 to 1.1). Post‐procedural esophagitis occurred in 20.7% and wrap integrity was preserved in 75.7% on follow‐up, supporting ...
Yusuf Kagzi, Abuzar Asif, Srinivas Reddy Puli   +2 more
wiley   +1 more source

Esophagus and Its Function Related to Gastro-esophageal Reflux [PDF]

, 2012
The main function of the esophagus is to transport food from the mouth into stomach. Anatomical structures, innervations and blood supplies are needed in order to transport the food into stomach.
Hegar, B. (Badriul), Reynaldo, A. (Aldo), Vandenplas, Y. (Yvan)   +2 more
core