LINX®, a novel treatment for patients with refractory asthma complicated by gastroesophageal reflux disease: a case report. [PDF]
BackgroundGastroesophageal reflux disease is one of the most common comorbidities in patients with asthma. Gastroesophageal reflux disease can be linked to difficult-to-control asthma.
Kenyon, Nicholas J+6 more
core +2 more sources
Treatment of esophageal achalasia in children: Today and tomorrow [PDF]
Esophageal achalasia (EA) is a rare esophageal motility disorder in children. Laparoscopic Heller myotomy (LHM) represents the treatment of choice in young patients. Peroral endoscopic myotomy (POEM) is becoming an alternative to LHM.
Caldaro, T+11 more
core +1 more source
A Mathematical model for the effect of Gastrin in humans using Fuzzy Rayleigh distribution [PDF]
Gastrin is a potent stimulant of lower esophageal sphincter pressure in human. Several observations suggest that lower esophageal sphincter pressure is under the control of gastrin concentration.
A. Venkatesh, G.. Subramani
core +1 more source
Morphology of the Esophageal Hiatus: Is It Different in 3 Types of Hiatus Hernias? [PDF]
Background/aimsThe esophageal hiatus is formed by the right crus of the diaphragm in the majority of subjects. Contraction of the hiatus exerts a sphincter-like action on the lower esophageal sphincter (LES). The aim is to study the hiatal anatomy (using
Ghahremani, Gary+5 more
core +1 more source
Investigation of cholecystokinin receptors in the human lower esophageal sphincter [PDF]
Aim: To compare the binding of cholecystokinin (CCK)-8 to CCK receptors in sling and clasp fibers of the human lower esophageal sphincter. Methods: Esophageal sling and clasp fibers were isolated from eight esophagectomy specimens, resected for squamous ...
Drew, P., Liu, J., Liu, X., Zhang, J.
core +1 more source
Quantitation of Lower Esophageal Sphincter Competence
Summary Normal subjects and patients with incompetent gastroesophageal sphincters have been studied by open-tipped catheter techniques. The two groups could not be separated on the basis of pressures measured by conventional methods. The best explanation for this failure is that the sphincters sealed the recording orifice.
Lauran D. Harris, Charles S. Winans
openaire +3 more sources
Esophageal Acalasia: Pathophysiology, Diagnosis and Management [PDF]
Achalasia is a rare disease, but it can lead to loss of the lower esophageal sphincter (LES) causing many complications in the gastrointestinal tract. Achalasia has a good prognosis if treated promptly, but the symptoms are non-specific.
Akelba, Shalsa Damai+4 more
core +1 more source
Can intraoperative manometry influence the outcome of the surgical treatment of achalasia? [PDF]
Introduction. Achalasia is defined as incomplete or even absent relaxation of the lower esophageal sphincter secondary to the chronic degeneration of unspecified etiology of the myenteric nerve plexus. Material and method.
Alecu, Lucian+5 more
core +1 more source
Development and Application of a Functional Human Esophageal Mucosa Explant Platform to Eosinophilic Esophagitis. [PDF]
There is an increasing prevalence of esophageal diseases but intact human tissue platforms to study esophageal function, disease mechanisms, and the interactions between cell types in situ are lacking.
Aceves, Seema S+12 more
core +3 more sources
Mechanics of Sphincter Action. STUDIES ON THE LOWER ESOPHAGEAL SPHINCTER [PDF]
The purpose of this study was to evaluate the mechanical factors involved in the genesis of lower esophageal sphincter pressure. We determined the relationship between intraluminal pressure and inside diameter, estimated the ratio between the wall thickness to inside radius, and calculated the tension in the wall of the lower esophageal sphincter as a ...
Aris Phillips+3 more
openaire +2 more sources