Results 191 to 200 of about 22,833 (219)
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Transient lower esophageal sphincter relaxation
Gastroenterology, 1995RAVINDER K. MITTAL,* RICHARD H. HOLLOWAY,* ROBERTO PENAGINI, § L. ASHLEY BLACKSHAW, t and JOHN DENT* *Department of Internal Medicine, University of Virginia, Charlottesville, Virginia; *Gastrointestinal Medicine, Royal Adelaide Hospital, Adelaide, South Australia, Australia; and §Cattedra di Gastroenterologia, Istituto di Scienze Mediche, University ...
R. K. Mittal +4 more
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Lower Esophageal Sphincter Pressure as an Index of Lower Esophageal Sphincter Strength
Gastroenterology, 1970The ability of pressures measured in the lower esophageal sphincter to assess accurately the strength of the sphincter cannot be evaluated without a suitable objective measurement of sphincter strength. This study describes a measurement of strength and compares it with sphincter pressure.
S, Cohen, L D, Harris
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Lower esophageal sphincter pressure in histologic esophagitis
Digestive Diseases and Sciences, 1980The fasting lower esophageal sphincter pressure of 18 normal volunteers was compared to 22 patients with symptoms and objective evidence of gastroesophageal reflux. Lower esophageal sphincter pressure was measured by rapid pull-through using an 8-lumen radially perfused catheter that sampled pressure every45 degrees around the circumference of the ...
R W, Welch +5 more
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Disorders of the Lower Esophageal Sphincter
Annual Review of Medicine, 1975The junction of the esophagus and stomach in man is marked by a zone of elevated pressure which has been called the lower esophageal sphincter (LES) (1, 2). The purpose of this sphincter mechanism is to prevent regurgitation of gastric contents from a positive pressure cavity into the esophagus which maintains a pressure negative to the atmosphere (3 ...
R S, Fisher, S, Cohen
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Lower Esophageal Sphincter Dysfunction in Achalasia
Gastroenterology, 1971In patients with achalasia, lower esophageal sphincter (LES) dysfunction plays an important role in the impairment of esophageal emptying. To evaluate this dysfunction, the manometric characteristics of the LES were recorded for 20 normals and for 16 patients with achalasia, both before and after pneumatic dilation.
S, Cohen, W, Lipshutz
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Pathogenesis of Lower-Esophageal-Sphincter Incompetence
New England Journal of Medicine, 1973Abstract Since patients with symptomatic gastroesophageal reflux have diminished lower-esophagealsphincter pressure, we studied the pathogenesis of this diminished sphincteric pressure. In 23 patients with symptomatic reflux as compared to 20 controls, the lower-esophageal-sphincter response to direct muscle stimulation by a parasympathomimetic drug ...
W H, Lipshutz +3 more
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The Lower Esophageal Sphincter
2014The lower esophageal sphincter (LES) is a complex area of circular muscle on the distal esophagus and proximal stomach several centimeters in length. Together with the diaphragmatic crura and the structure of the angle of His, the LES makes up the backbone of the gastroesophageal reflux barrier.
Christina L. Greene, Steven R. DeMeester
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The Lower Esophageal Sphincter
Annals of Internal Medicine, 1975Current concepts in physiology and pathophysiology of lower esophageal sphincteric mechanism are reviewed. With recent advances in manometric method for more accurate in-vivo human studies combined with in-vivo and in-vitro studies in animal models, there is much information regarding function of this sphincter.
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Distinction of lower esophageal sphincter strength from sphincter competence
The American Journal of Surgery, 1987Although an absolute correlation has been impossible to demonstrate, it has long been thought that the manometric magnitude of the lower esophageal sphincter pressure was a good index of lower esophageal sphincter strength, and hence its competence. To study this relationship, 12 adult mongrel cats were surgically fitted with gastric cannulas. The cats
T R, McLean, C T, Bombeck, L M, Nyhus
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Lower-esophageal sphincter function does not determine resting upper-esophageal sphincter pressure
The American Journal of Digestive Diseases, 1977Records of 269 esophageal motility studies were reviewed to determine the relationship between lower-esophageal sphincter (LES) function and upper-esophageal sphincter (UES) pressure. Average and greatest UES pressures were similar in patients with LES pressures less than 10 mm Hg or greater than 20 mm Hg, and in patients with and without ...
L E, Berte, C S, Winans
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