Role of differentially expressed microRNA-139-5p in the regulation of phenotypic internal anal sphincter smooth muscle tone. [PDF]
The present study focused on the role of microRNA-139-5p (miRNA-139-5p) in the regulation of basal tone in internal anal sphincter (IAS). Applying genome-wide miRNA microarrays on the phenotypically distinct smooth muscle cells (SMCs) within the rat ...
Addya, Sankar+7 more
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Regurgitation in healthy and non healthy infants [PDF]
Uncomplicate regurgitation in otherwise healthy infants is not a disease. It consists of milk flow from mouth during or after feeding. Common causes include overfeeding, air swallowed during feeding, crying or coughing; physical exam is normal and weight
CAVALLO L+5 more
core +3 more sources
Muscular Equivalent of the Lower Esophageal Sphincter
In order to measure muscle thickness and to define the muscular architecture at the gastroesophageal function, both en bloc fixation and a new method of preparing dried fiber specimens were used. Specimens were obtained from 32 kidney donors and human cadavers. Wall thickness was measured at 32 identical locations in the esophagus and stomach.
Paul Schmid+3 more
openaire +3 more sources
Dietary guideline adherence for gastroesophageal reflux disease. [PDF]
BackgroundGastroesophageal reflux disease (GERD) is the most common gastrointestinal disease, and the cost of health care and lost productivity due to GERD is extremely high.
Block, Gladys+4 more
core +2 more sources
The Action of a Carminative on the Lower Esophageal Sphincter
The effect of essence of peppermint on the lower esophageal sphincter was studied manometrically in 27 subjects. In 25 subjects, within 1 to 7 min following the introduction of the peppermint, a decrease in intrasphincteric pressure was noted. When intrasphincteric pressure approximated intragastric pressure, there was an increase in intraesophageal ...
Charles J. Sigmund, Edmund F. McNally
openaire +3 more sources
Outcomes of esophageal surgery, especially of the lower esophageal sphincter [PDF]
This paper includes commentaries on outcomes of esophageal surgery, including the mechanisms by which fundoduplication improves lower esophageal sphincter (LES) pressure; the efficacy of the Linx™ management system in improving LES function; the utility of radiologic characterization of antireflux valves following surgery; the correlation between ...
L. Bonavina+9 more
openaire +2 more sources
An investigation of the progression from Barrett's esophagus to adenocarcinoma [PDF]
Barrett's esophagus is a metaplasia of the epithelium of the lower esophagus from a normal squamous appearance to a columnar appearance more typically found in the stomach. It is normally caused by prolonged gastric reflux. While Barrett's esophagus is
Palmese, Scott Joseph
core +1 more source
Not All Children with Cystic Fibrosis Have Abnormal Esophageal Neutralization during Chemical Clearance of Acid Reflux. [PDF]
PurposeAcid neutralization during chemical clearance is significantly prolonged in children with cystic fibrosis, compared to symptomatic children without cystic fibrosis.
Di Lorenzo, Carlo+9 more
core +3 more sources
Megaesophagus in a Line of Transgenic Rats: A Model of Achalasia [PDF]
Megaesophagus is defined as the abnormal enlargement or dilatation of the esophagus, characterized by a lack of normal contraction of the esophageal walls.
Borjeson, Tiffany M.+10 more
core +1 more source
The gastric acid pocket is attenuated in H. pylori infected subjects [PDF]
Objective Gastric acid secretory capacity in different anatomical regions, including the postprandial acid pocket, was assessed in Helicobacter pylori positive and negative volunteers in a Western population. Design We studied 31 H.
Ballantyne, Stuart A.+6 more
core +1 more source