Esophageal sphincter device for gastroesophageal reflux disease [PDF]
BACKGROUND Patients with gastroesophageal reflux disease who have a partial response to proton-pump inhibitors often seek alternative therapy. We evaluated the safety and effectiveness of a new magnetic device to augment the lower esophageal sphincter ...
Bemelman, Willem A+14 more
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Bile acids cause relaxation of the lower esophageal sphincter through G-protein-coupled bile acid receptors [PDF]
ObjectivesBile acids inhibit contraction of the gallbladder and intestine through the G-protein-coupled bile acid receptor (GPBAR). Perfusion of the esophagus with bile and acid (HCl) decreases lower esophageal sphincter (LES) pressure.
Huang, Shih-Che
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Role of High total protein in gallbladder bile in the formation of cholesterol gallstones. [PDF]
While it is generally accepted that cholesterol supersaturation of bile is of key importance in the rapid formation of cholesterol crystals, the role of total biliary protein and pH in the pathogenesis of cholesterol gallstones is less well understood ...
Abell+37 more
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The prevalence of gastro-esophageal reflux disease and esophageal dysmotility in Chinese patients with idiopathic pulmonary fibrosis [PDF]
BACKGROUND: The cause of idiopathic pulmonary fibrosis (IPF) remains unknown, yet gastro-esophageal reflux disease (GERD) is highly prevalent in this population.
Anthony Robert Hobson+6 more
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Smooth muscle fascicular reorientation is required for esophageal morphogenesis and dependent on Cdo. [PDF]
Postnatal maturation of esophageal musculature involves proximal-to-distal replacement of smooth muscle with skeletal muscle by elusive mechanisms. We report that this process is impaired in mice lacking the cell surface receptor Cdo and identify the ...
Anthony I. Romer+40 more
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Esophageal Tandem Stenting above the Lower Esophageal Sphincter
AbstractFully covered esophageal metal stents can be used for the conservative management of esophageal leaks, perforations, and fistulas. However, the risk of stent migration is high. The authors present a case of tandem esophageal stenting above the lower esophageal sphincter (LES) by taking advantage of the natural anchorage offered by the LES, with
S-J Tang, S. R. Daram
openaire +2 more sources
Opioid-induced Lower Esophageal Sphincter Dysfunction
The adverse gastrointestinal effects of opioids have been extensively described in medical literature.1 Their effect takes place mainly on the enteric nervous system, through receptors in the myenteric and submucosal plexuses. There are 3 recognized main opium receptors (μ, δ, and κ) that are expressed in the central and enteric nervous systems, which ...
Vicente Garrigues Gil+4 more
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Gastroesophageal Reflux Disease: An Overview [PDF]
The following is an excerpt of the introduction of this article: There are many well-known disorders associated with the digestion process, the most common of which is gastroesophageal reflux disease, more commonly known as GERD.
Eckstein, Mayer
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Patulous Lower Esophageal Sphincter [PDF]
Peter C. Belafsky, Catherine J. Rees
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Role of gastrin supersensitivity in the pathogenesis of lower esophageal sphincter hypertension in achalasia [PDF]
Sidney Cohen+2 more
openalex +1 more source