Results 211 to 220 of about 5,195,127 (254)

Ovarian Cancer: Epidemiology, Disease Mechanisms, New Diagnosis and Treatment Strategies, and Research Directions

iNew Medicine, EarlyView.
ABSTRACT Ovarian cancer (OC) continues to be the deadliest gynecological malignancy and a significant cause of cancer‐related mortality among women worldwide. Standard treatment strategies typically entail platinum‐based chemotherapy in conjunction with cytoreductive surgery.
Zunera Khalid, Weirong Fan, Farah Nazir, Yixiang Xing, Tengchuan Jin   +4 more
wiley   +1 more source

Gastrointestinal bleeding in patients on venoarterial extracorporeal membrane oxygenation: a multicenter observational study. [PDF]

BMC Gastroenterol
Zhang Z, Zhu Y, Zhang G, You X, Dong Y, Hu D, Sun H, Li W, Chen X.   +8 more
europepmc   +1 more source

Hepatic Encephalopathy and Age Were Assessed to Ameliorate the Underestimation of the Model for End‐Stage Liver Disease Score in Patients With Acute‐on‐Chronic Liver Failure

iNew Medicine, EarlyView.
This study demonstrates that the model for end‐stage liver disease (MELD) score significantly underestimates 90‐day mortality in acute‐on‐chronic liver failure (ACLF) patients (AUC: 0.556) compared to non‐ACLF patients (area under the receiver operating characteristic curve [AUC]: 0.848).
Guanghou Chen, Qifei Guan, Yufeng Gao, Zhenhua Zhang, Hongchuan Zhao, Beicheng Sun   +5 more
wiley   +1 more source

Direct oral anticoagulants in elderly patients with atrial fibrillation: a decade-long nationwide retrospective cohort study. [PDF]

BMJ Open
Alnsasra H, Tsaban G, Ostrovsky D, Livne N, Filderman B, Henkin Y, Iakobishvili Z, Arnson Y, Eisen A, Weisband Y, Schliamser J, Haim M.   +11 more
europepmc   +1 more source

Microbial metabolite indole‐3‐propionic acid preserves astrocytic mitochondrial mitofusin 2 to limit neuroinflammation after traumatic brain injury

Interdisciplinary Medicine, EarlyView.
Following traumatic brain injury, indole‐3‐propionic acid (IPA) directly targets the aryl hydrocarbon receptor on astrocytes in the peri‐lesional cortex; this suppresses interferon regulatory factor 1‐driven transcription of the E3 ubiquitin ligase RFFL (ring finger and FYVE‐like domain containing E3 ubiquitin protein ligase).
Ziwen Zhang, Kai Wang, Liangbo Wang, Wencong Li, Hao Guo, Meng Xu, Tinghao Wang, Jiahui Ren, Ting Zhu, Jiahui Wang, Wenxing Cui, Jinpeng Zhou, Yang Tian, Liying Han, Chengxuan Guo, Shuoyao Ma, Qiang Wang, Zhihong Li, Yaning Cai, Jingyu Dong, Xun Wu, Haixiao Liu, Yan Qu   +22 more
wiley   +1 more source

Postbleeding antithrombotic management in cardiovascular patients: insights from the Attica Bleeding Snapshot study. [PDF]

Res Pract Thromb Haemost
Soulaidopoulos S, Leontsinis I, Chrysochoou C, Dri E, Tatakis F, Kyriazis I, Skopelitis E, Sevastianos V, Korompoki E, Touliatou A, Paraskeva K, Vallianou NG, Tsiodras S, Psyrri A, Manolakopoulos S, Papatheodoridis G, Vassilopoulos D, Tentolouris N, Tsioufis K, Centers and Investigators.   +19 more
europepmc   +1 more source

The Effects of Angiotensin Receptor Neprilysin Inhibitor on Endoplasmic Reticulum Stress in Doxorubicin‐Mediated Cardiomyopathy‐Associated Heart Failure Model in Rats

Journal of Applied Toxicology, EarlyView.
ABSTRACT One of the most serious complications associated with the use of the chemotherapeutic agent doxorubicin (DOX) is cardiomyopathy. Although cardioprotective drugs such as angiotensin receptor‐neprilysin inhibitors (ARNI) are used to prevent cardiomyopathy in DOX patients, no studies have reported the relationship between ARNI and endoplasmic ...
Mert Unvan, Meryem İlkay Karagül, Hatice Oruç Demirbağ, Ebru Balli   +3 more
wiley   +1 more source

Splenic Artery Embolization, A Therapy that Can be Life-Saving for Small Bowel Variceal Bleeding. [PDF]

Eur J Case Rep Intern Med
Radwan R, Ghantous M, Salem J, Khoury J, Geagea A, Chidiac K.   +5 more
europepmc   +1 more source

Toxic Effects of Bisphenol A and Its Analogs on Ovarian Structure and Function: A Narrative Review of Ovary‐Focused Studies

Journal of Applied Toxicology, EarlyView.
ABSTRACT Bisphenol A (BPA) is a widely used industrial chemical found in polycarbonate plastics and epoxy resins and is recognized for its endocrine‐disrupting properties. Human exposure is common due to its presence in food packaging and everyday products. As BPA use has been restricted, structurally similar compounds such as BPS, BPB, BPAF, and BADGE
Nurbanu Zengin, Marwa Tawfıq Ahmed Alsalım, Muhammed Canik, Sevda Bağdatlı, Nazan Deniz Yön   +4 more
wiley   +1 more source

Transarterial Embolization for Malignancy-Related Gastrointestinal Bleeding: Outcomes with and Without CT Extravasation. [PDF]

Diagnostics (Basel)
Cho KK, Lee BC, Kim HO, Park C, Choi IW, Angle JF.   +5 more
europepmc   +1 more source